1,2-Pyrrolidinedicarboxylic acid, 5-(2-propen-1-yl)-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)-

Base Information

Chemical Name:1,2-Pyrrolidinedicarboxylic acid, 5-(2-propen-1-yl)-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)-
CAS No.:291517-55-0
Molecular Formula:C₁₅H₂₅NO₄
Molecular Weight:283.368
Hs Code.:2933990090
Mol file:291517-55-0.mol

Synonyms:1,2-Pyrrolidinedicarboxylic acid, 5-(2-propen-1-yl)-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)-

Suppliers and Price of 1,2-Pyrrolidinedicarboxylic acid, 5-(2-propen-1-yl)-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2S)-1-tert-Butyl2-ethyl5-allylpyrrolidine-1,2-dicarboxylate 95+%
1g
$ 668.00

Chemenu
1-(tert-butyl)2-ethyl(2S)-5-allylpyrrolidine-1,2-dicarboxylate 95%
1g
$ 631.00

American Custom Chemicals Corporation
(2S)-1-TERT-BUTYL-2-ETHYL 5-ALLYLPYRROLIDINE-1,2-DICARBOXYLATE 95.00%
1G
$ 1379.70

American Custom Chemicals Corporation
(2S)-1-TERT-BUTYL-2-ETHYL 5-ALLYLPYRROLIDINE-1,2-DICARBOXYLATE 95.00%
5MG
$ 502.69

Alichem
(2S)-1-tert-Butyl2-ethyl5-allylpyrrolidine-1,2-dicarboxylate
1g
$ 560.32

Total 4 raw suppliers

Chemical Property of 1,2-Pyrrolidinedicarboxylic acid, 5-(2-propen-1-yl)-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)-

Chemical Property:

PSA：55.84000
LogP:2.83160
Storage Temp.:2-8°C

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

(2S)-1-tert-Butyl2-ethyl5-allylpyrrolidine-1,2-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,2-Pyrrolidinedicarboxylic acid, 5-(2-propen-1-yl)-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)-

There total 7 articles about 1,2-Pyrrolidinedicarboxylic acid, 5-(2-propen-1-yl)-, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 291517-54-9
(2S,5R/S)-1-(tert-butyloxycarbonyl-5-ethoxy)-proline ethyl ester

: 762-72-1
allyl-trimethyl-silane

: 291517-55-0
ethyl (2S,5R/S)-1-(tert-butyloxycarbonyl-5-allyl)-prolinate

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at -90 ℃;
DOI:10.1016/S0040-4020(00)00355-0

Reference yield:

: 24850-33-7
allyltributylstanane

: 194594-23-5
5-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester

: 291517-55-0
ethyl (2S,5R/S)-1-(tert-butyloxycarbonyl-5-allyl)-prolinate

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; for 2h;
DOI:10.1039/b605293b

Reference yield:

: 144978-35-8,144978-12-1,251924-83-1
(S)-ethyl N-tert-butoxycarbonylpyroglutamate

: 291517-55-0
ethyl (2S,5R/S)-1-(tert-butyloxycarbonyl-5-allyl)-prolinate

Guidance literature:: Multi-step reaction with 2 steps

1: LiEt₃BH / tetrahydrofuran / 1 h / -78 °C

2: 0.217 g / BF₃*OEt₂ / CH₂Cl₂ / 2 h / -78 °C

With boron trifluoride diethyl etherate; lithium triethylborohydride; In tetrahydrofuran; dichloromethane;
DOI:10.1039/b605293b