2-BROMOISONICOTINOYL CHLORIDE

Base Information

• Chemical Name: 2-BROMOISONICOTINOYL CHLORIDE
• CAS No.: 887578-70-3
• Molecular Formula: C₆H₃BrClNO
• Molecular Weight: 220.453
• Hs Code.: 2933399090
• Mol file: 887578-70-3.mol

Synonyms:2-BROMOISONICOTINOYL CHLORIDE;4-PYRIDINECARBONYL CHLORIDE, 2-BROMO-

Chemical Property of 2-BROMOISONICOTINOYL CHLORIDE

Chemical Property:

• PSA: 29.96000
• LogP: 2.22310

Purity/Quality:

99%, ^*data from raw suppliers

2-Bromoisonicotinoyl chloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMOISONICOTINOYL CHLORIDE

There total 1 articles about 2-BROMOISONICOTINOYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromoisonicotinic acid (66572-56-3) → 2-bromoisonicotinoyl chloride (887578-70-3)

Guidance literature:

With thionyl chloride; for 1.5h; Heating / reflux;

Reference yield:

2-bromoisonicotinoyl chloride (887578-70-3) → 2-(isoquinolin-4-ylethynyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)isonicotinamide

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 5 h / 0 - 20 °C

2: copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; cesium fluoride / acetonitrile / 0.33 h / 20 - 90 °C / Inert atmosphere; Irradiation

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; cesium fluoride; In dichloromethane; acetonitrile;

DOI:10.1016/j.ejmech.2016.10.003

upstream raw materials:

2-bromoisonicotinic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 887578-70-3 2-BROMOISONICOTINOYL CHLORIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send