2,4,5-Tribromopyridine

Base Information

• Chemical Name: 2,4,5-Tribromopyridine
• CAS No.: 856857-52-8
• Molecular Formula: C5H2Br3N
• Molecular Weight: 315.79
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID50355739
• Wikidata: Q82134793
• Mol file: 856857-52-8.mol

Synonyms:2,4,5-tribromopyridine;856857-52-8;DTXSID50355739;AKOS015946344;BS-29503;CS-0207826;AC-907/25004327

Chemical Property of 2,4,5-Tribromopyridine

Chemical Property:

• PSA: 12.89000
• LogP: 3.36910
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 314.77169
• Heavy Atom Count: 9
• Complexity: 98.2

Purity/Quality:

99% ^*data from raw suppliers

2,4,5-TRIBROMOPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(C(=CN=C1Br)Br)Br

Technology Process of 2,4,5-Tribromopyridine

There total 3 articles about 2,4,5-Tribromopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.0%

pentabromopyridine (2402-94-0) → 2,4,6-tribromopyridine (856857-52-8) + 2,3,4,6-tetrabromo-pyridine (101252-31-7)

Guidance literature:

In diethyl ether; for 41h; Irradiation;

Reference yield:

3,5-dibromo-2,4-dihydroxypyridine (80791-78-2) → 2,4,6-tribromopyridine (856857-52-8)

Guidance literature:

With hydrogen bromide; at 200 ℃; Erhitzen des Reaktionsprodukts mit Phosphorylbromid auf 160grad;

Reference yield:

3-deazauracil (626-03-9,84719-31-3) → 2,4,6-tribromopyridine (856857-52-8)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated aqueous hydrobromic acid; acetic acid; bromine

2: aqueous hydrobromic acid / 200 °C / Erhitzen des Reaktionsprodukts mit Phosphorylbromid auf 160grad

With hydrogen bromide; bromine; acetic acid;

upstream raw materials:

3,5-dibromo-2,4-dihydroxypyridine

pentabromopyridine

3-deazauracil

Downstream raw materials:

2,5-dibromo-[4]pyridylamine

Refernces