9-[(2R)-3α-Hydroxy-4β-(hydroxymethyl)tetrahydrofuran-2β-yl]-9H-purine-6-amine

Base Information

Chemical Name:9-[(2R)-3α-Hydroxy-4β-(hydroxymethyl)tetrahydrofuran-2β-yl]-9H-purine-6-amine
CAS No.:19200-56-7
Molecular Formula:C10H13N5O3
Molecular Weight:251.24
Hs Code.:
Mol file:19200-56-7.mol

Synonyms:9-[(2R)-3α-Hydroxy-4β-(hydroxymethyl)tetrahydrofuran-2β-yl]-9H-purine-6-amine

Suppliers and Price of 9-[(2R)-3α-Hydroxy-4β-(hydroxymethyl)tetrahydrofuran-2β-yl]-9H-purine-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 9-[(2R)-3α-Hydroxy-4β-(hydroxymethyl)tetrahydrofuran-2β-yl]-9H-purine-6-amine

Chemical Property:

Melting Point:212 - 213 °C
PSA：119.31000
LogP:-0.51210

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 9-[(2R)-3α-Hydroxy-4β-(hydroxymethyl)tetrahydrofuran-2β-yl]-9H-purine-6-amine

There total 14 articles about 9-[(2R)-3α-Hydroxy-4β-(hydroxymethyl)tetrahydrofuran-2β-yl]-9H-purine-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 448896-47-7
9-((1R,2R,3S)-tetrahydro-2-hydroxy-3-(((4-methoxyphenyl)-diphenylmethoxy)-methyl)-1-furanyl)-9H-adenine

: 19200-56-7
9-((1R,2R,3S)-tetrahydro-2-hydroxy-3-(hydroxymethyl)-1-furanyl)-9H-adenine

Guidance literature:: With acetic acid; at 20 ℃; for 5h;
DOI:10.1007/s007060200024

Reference yield: 88.0%

: 1374011-57-0
1'-(adenin-9-yl)-3'-deoxy-5'-O-benzyl-β-D-apio-D-furanose

: 19200-56-7
9-((1R,2R,3S)-tetrahydro-2-hydroxy-3-(hydroxymethyl)-1-furanyl)-9H-adenine

Guidance literature:: 1'-(adenin-9-yl)-3'-deoxy-5'-O-benzyl-β-D-apio-D-furanose; With formic acid; Pd(OH)2/C; In methanol; at 55 ℃; Inert atmosphere;

With ammonia; In methanol; at 25 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jo500659e

Reference yield:

: 287933-80-6
6-N-benzoyl-9-((1R,2R,3S)-tetrahydro-2-acetoxy-3-(((4-methoxyphenyl)-diphenylmethoxy)-methyl)-1-furanyl)-9H-adenine

: 19200-56-7
9-((1R,2R,3S)-tetrahydro-2-hydroxy-3-(hydroxymethyl)-1-furanyl)-9H-adenine

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / sat. aq. NH₃ / methanol / 24 h / 20 °C

2: 100 percent / aq. AcOH / 5 h / 20 °C

With ammonium hydroxide; acetic acid; In methanol;
DOI:10.1007/s007060200024