6-Ethoxy-5-fluoropyridine-3-boronic acid pinacol ester

Base Information

Chemical Name:6-Ethoxy-5-fluoropyridine-3-boronic acid pinacol ester
CAS No.:1334167-86-0
Molecular Formula:C₁₃H₁₉BFNO₃
Molecular Weight:267.108
Hs Code.:2934999090
Mol file:1334167-86-0.mol

Synonyms:6-Ethoxy-5-fluoropyridine-3-boronic acid pinacol ester;2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Suppliers and Price of 6-Ethoxy-5-fluoropyridine-3-boronic acid pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95+%
1g
$ 975.00

Matrix Scientific
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95+%
250mg
$ 439.00

Crysdot
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95+%
1g
$ 455.00

Chemenu
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95%
1g
$ 416.00

American Custom Chemicals Corporation
2-ETHOXY-3-FLUORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 95.00%
1G
$ 975.45

American Custom Chemicals Corporation
2-ETHOXY-3-FLUORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 95.00%
5MG
$ 497.62

Alichem
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
1g
$ 400.00

AK Scientific
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
250mg
$ 642.00

Total 6 raw suppliers

Chemical Property of 6-Ethoxy-5-fluoropyridine-3-boronic acid pinacol ester

Chemical Property:

Boiling Point:336.1±42.0 °C(Predicted)
PKA:1.59±0.34(Predicted)
PSA：40.58000
Density:1.10±0.1 g/cm3(Predicted)
LogP:1.91860
Storage Temp.:2-8°C

Purity/Quality:

98% ^*data from raw suppliers

2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-Ethoxy-5-fluoropyridine-3-boronic acid pinacol ester

There total 3 articles about 6-Ethoxy-5-fluoropyridine-3-boronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 886373-94-0
5-chloro-2-ethoxy-3-fluoro-pyridine

: 73183-34-3
bis(pinacol)diborane

: 1334167-86-0
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; In 1,4-dioxane; at 20 - 85 ℃; for 20h; Inert atmosphere;

Reference yield:

: 89402-43-7
5-chloro-2,3-difluoropyridine

: 1334167-86-0
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 16 h / 80 °C

2: potassium phosphate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / palladium diacetate / 1,4-dioxane / 20 h / 20 - 85 °C / Inert atmosphere

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; In 1,4-dioxane;

Reference yield:

: 1334167-86-0
2-Ethoxy-3-fluoro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 80 ℃; for 1h; Inert atmosphere; Microwave irradiation;