4,6,7-Trichloroquinoline

Base Information

Chemical Name:4,6,7-Trichloroquinoline
CAS No.:855763-18-7
Molecular Formula:C9H4Cl3N
Molecular Weight:232.496
Hs Code.:2933499090
European Community (EC) Number:804-452-7
DSSTox Substance ID:DTXSID50589017
Wikidata:Q82482098
Mol file:855763-18-7.mol

Synonyms:4,6,7-Trichloroquinoline;855763-18-7;4-CHLORO-6,7-DICHLOROQUINOLINE;SCHEMBL6004219;DTXSID50589017;MFCD08063228;4,6,7-Trichloroquinoline, AldrichCPR;AB43475;DB-425715;CS-0366511;EN300-8167186

Suppliers and Price of 4,6,7-Trichloroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4,6,7-Trichloroquinoline
1 g
$ 456.00

Sigma-Aldrich
4,6,7-Trichloroquinoline Aldrich
1g
$ 258.00

Crysdot
4-Chloro-6,7-dichloroquinoline 95+%
1g
$ 406.00

Chemenu
4-Chloro-6,7-dichloroquinoline 95%
1g
$ 383.00

American Custom Chemicals Corporation
4-CHLORO-6,7-DICHLOROQUINOLINE 95.00%
5MG
$ 496.36

Alichem
4,6,7-Trichloroquinoline
1g
$ 455.10

Alichem
4,6,7-Trichloroquinoline
250mg
$ 167.28

Total 5 raw suppliers

Chemical Property of 4,6,7-Trichloroquinoline

Chemical Property:

Vapor Pressure:0.000668mmHg at 25°C
Boiling Point:318.6°C at 760 mmHg
Flash Point:175.9°C
PSA：12.89000
Density:1.523g/cm³
LogP:4.19500
Storage Temp.:Room Temperature, under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:230.940932
Heavy Atom Count:13
Complexity:188

Purity/Quality:

98%min ^*data from raw suppliers

4,6,7-Trichloroquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25-41
Safety Statements: 26-39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C2C=C(C(=CC2=C1Cl)Cl)Cl

Technology Process of 4,6,7-Trichloroquinoline

There total 4 articles about 4,6,7-Trichloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

: 15568-85-1
5-methoxymethylene-2,2-dimethyl-1,3-dioxane-4,6-dione

: 95-76-1
m,p-dichloroaniline

: 855763-18-7
4,6,7-trichloroquinoline

: 855763-30-3
4,5,6-trichloro-quinoline

Guidance literature:: 5-methoxymethylene-2,2-dimethyl-1,3-dioxane-4,6-dione; m,p-dichloroaniline; In diphenylether; at 70 ℃; for 0.5h;

In diphenylether; biphenyl; at 220 ℃; for 1h;

With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 100 ℃; for 1h;

Reference yield:

: 95-76-1
m,p-dichloroaniline

: 108-56-5
diethyl oxaloacetate

: 855763-18-7
4,6,7-trichloroquinoline

: 855763-30-3
4,5,6-trichloro-quinoline

Guidance literature:: With acetic acid; mineral oil; at 250 ℃; Erh_. des Gem_. aus 5,6-Dichlor-4-hydroxy-chinolin-2-carbonsaeure-aethylester u. 6,7-Dichlor-4-hydroxy-chinolin-2-carbonsaeure-aethylester mit wss. NaOH, anschl. Erh_. in Mineraloel auf 270grad, Erh_. des Rktprod_. mit Phosphorylchlorid;
DOI:10.1021/ja01211a030

Reference yield:

: 909344-70-3
5-[(3,4-dichloro-phenylamino)-methylene]-2,2-dimethyl-[1,3]dioxane-4,6-dione

: 855763-18-7
4,6,7-trichloroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: diphenyl ether / 0.08 h / 300 °C / microwave irradiation

2: POCl₃ / 3 h / Heating

With trichlorophosphate; In diphenylether;
DOI:10.1016/j.bmcl.2004.12.037