2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate)

Base Information

Chemical Name:2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate)
CAS No.:199014-22-7
Molecular Formula:C11H15NO8S2
Molecular Weight:353.3687
Hs Code.:
Mol file:199014-22-7.mol

Synonyms:2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate)

Suppliers and Price of 2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
2-(2-(methylsulfonyloxy)ethyl)-4-nitrobenzylmethanesulfonate
100mg
$ 155.00

Total 7 raw suppliers

Chemical Property of 2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate)

Chemical Property:

Boiling Point:632.1±55.0 °C(Predicted)
PSA：149.32000
Density:1.483±0.06 g/cm3(Predicted)
LogP:3.27450

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-(methylsulfonyloxy)ethyl)-4-nitrobenzylmethanesulfonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate)

There total 6 articles about 2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (Methanesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 124-63-0
methanesulfonyl chloride

: 186390-74-9
2-(2-Hydroxymethyl-5-nitro-phenyl)-ethanol

: 199014-22-7
[2-[2-[(methylsulfonyl)oxy]ethyl]-4-nitrophenyl]methyl methanesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at -30 ℃; for 0.5h;
DOI:10.1080/00397919908085813

Reference yield:

: 99-60-5
2-chloro-4-nitrobenzoic acid

: 199014-22-7
[2-[2-[(methylsulfonyl)oxy]ethyl]-4-nitrophenyl]methyl methanesulfonate

Guidance literature:: Multi-step reaction with 5 steps

1: 70 percent / CuBr, NaOMe / 24 h / 70 °C

2: NaOH / methanol; H₂O / 3 h / Ambient temperature

3: ethyl acetate / 6 h / 65 °C

4: 89 percent / NaBH₄, BF₃*Et₂O / tetrahydrofuran / 16 h / 25 °C

5: Et₃N / CH₂Cl₂ / 0.5 h / below 0 deg C

With sodium hydroxide; sodium tetrahydroborate; boron trifluoride diethyl etherate; sodium methylate; triethylamine; copper(I) bromide; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate;
DOI:10.1021/jo972184e

Reference yield:

: 39585-32-5
2-carboxymethyl-4-nitro-benzoic acid

: 199014-22-7
[2-[2-[(methylsulfonyl)oxy]ethyl]-4-nitrophenyl]methyl methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / NaBH₄, BF₃*Et₂O / tetrahydrofuran / 16 h / 25 °C

2: Et₃N / CH₂Cl₂ / 0.5 h / below 0 deg C

With sodium tetrahydroborate; boron trifluoride diethyl etherate; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo972184e