(S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride

Base Information

• Chemical Name: (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride
• CAS No.: 1364632-45-0
• Molecular Formula: C4H11ClN2O
• Molecular Weight: 138.59594
• Mol file: 1364632-45-0.mol

Synonyms:(S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride;(3S)-tetrahydrofuran-3-ylhydrazine hydrochloride;[(3S)-Tetrahydro-3-furanyl]hydrazine hydrochloride

Chemical Property of (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride

Chemical Property:

• PSA: 47.28000
• LogP: 1.13180

Purity/Quality:

97% ^*data from raw suppliers

(3S)-(Tetrahydro-furan-3-yl)-hydrazinehydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride

There total 4 articles about (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.81%

(S)-tri-tert-butyl 2-(tetrahydrofuran-3-yl)hydrazine-1,1,2-tricarboxylate → [(3S)-tetrahydrofuran-3-yl]hydrazine hydrochloride (1364632-45-0)

Guidance literature:

With hydrogenchloride; In methanol; at 0 - 25 ℃; Temperature; Concentration;

Reference yield:

(-)-benzyl 2-(tetrahydrofuran-3-yl)hydrazinecarboxylate (1429510-92-8) → [(3S)-tetrahydrofuran-3-yl]hydrazine hydrochloride (1364632-45-0)

Guidance literature:

(-)-benzyl 2-(tetrahydrofuran-3-yl)hydrazinecarboxylate; With di-tert-butyl dicarbonate; palladium on activated charcoal; hydrogen; In methanol; at 25 ℃; for 48h; under 775.743 Torr;

With hydrogenchloride; In di-isopropyl ether; at 0 - 10 ℃;

Reference yield:

(S)-t-butyl 1-(tetrahydrofuran-3-yl)hydrazinecarboxylate (1429510-48-4) → [(3S)-tetrahydrofuran-3-yl]hydrazine hydrochloride (1364632-45-0)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 10 - 50 ℃; for 2.41667h;

upstream raw materials:

(S)-t-butyl 1-(tetrahydrofuran-3-yl)hydrazinecarboxylate

(-)-benzyl 2-(tetrahydrofuran-3-yl)hydrazinecarboxylate

(R)-3-Hydroxytetrahydrofuran

Downstream raw materials:

ethyl 5-(4-bromo-2,5-difluorophenyl)-1-[(S)-tetrahydrofuran-3-yl]-1H-pyrazole-4-carboxylate

ethyl 5-(4-bromo-2-fluorophenyl)-1-[(S)-tetrahydrofuran-3-yl]-1H-pyrazole-4-carboxylate

ethyl 5-(4-bromo-2-nitrophenyl)-1-[(S)-tetrahydrofuran-3-yl]-1H-pyrazole-4-carboxylate