tert-butyl 3-broMo-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

Base Information

Chemical Name:tert-butyl 3-broMo-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate
CAS No.:1393546-06-9
Molecular Formula:C12H15BrN2O2
Molecular Weight:299.167
Hs Code.:
Mol file:1393546-06-9.mol

Synonyms:tert-butyl 3-broMo-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate;Tert-butyl 3-bromo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate

Suppliers and Price of tert-butyl 3-broMo-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-3-BROMO-5,7-DIHYDRO-6H-PYRROLO[3,4-B]PYRIDINE-6-CARBOXYLATE 95.00%
5MG
$ 496.98

AK Scientific
Tert-butyl3-bromo-5H-pyrrolo[3,4-B]pyridine-6(7H)-carboxylate
1g
$ 816.00

Total 10 raw suppliers

Chemical Property of tert-butyl 3-broMo-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

Chemical Property:

Boiling Point:354.0±42.0 °C(Predicted)
PKA:2.81±0.20(Predicted)
PSA：42.43000
Density:1.450±0.06 g/cm3(Predicted)
LogP:3.03270

Purity/Quality:

97% ^*data from raw suppliers

TERT-BUTYL-3-BROMO-5,7-DIHYDRO-6H-PYRROLO[3,4-B]PYRIDINE-6-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 3-broMo-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

There total 6 articles about tert-butyl 3-broMo-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1393546-06-9
3-bromo-6-(tert-butoxycarbonyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 905273-36-1
3-bromo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

: 1393546-06-9
3-bromo-6-(tert-butoxycarbonyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 1h;

Reference yield:

: 583-61-9
2,3-Lutidine

: 1393546-06-9
3-bromo-6-(tert-butoxycarbonyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: sulfuric acid / 150 °C

1.2: 20 °C

2.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 4 h / 82 °C

3.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2.5 h / 60 °C

4.1: trifluoroacetic acid / methanol; chloroform / 0.6 h / 0 °C

5.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); sulfuric acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In methanol; tetrachloromethane; dichloromethane; chloroform; N,N-dimethyl-formamide;