Azd-4877

Base Information

Chemical Name:Azd-4877
CAS No.:1176760-49-8
Molecular Formula:C28H33N5O2S
Molecular Weight:503.65892
Hs Code.:
UNII:19ORU63E06
DSSTox Substance ID:DTXSID301026070
Wikidata:Q27074751
NCI Thesaurus Code:C64522
Pharos Ligand ID:YSW187L6F3PT
Metabolomics Workbench ID:152788
ChEMBL ID:CHEMBL1829433
Mol file:1176760-49-8.mol

Synonyms:AZD 4877;AZD-4877;AZD4877;N-(3-aminopropyl)-N-(1-(5-benzyl-3-methyl-4-oxo-(1,2)thiazolo(5,4-d)pyrimidin-6-yl)-2-methylpropyl)-4-methylbenzamide

Suppliers and Price of Azd-4877

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Azd-4877

Chemical Property:

PSA：122.35000
LogP:5.40670
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:503.23549649
Heavy Atom Count:36
Complexity:791

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C(=NS3)C)C(=O)N2CC4=CC=CC=C4)C(C)C
Recent ClinicalTrials:Phase I, Open-label, Dose Escalation of AZD4877 in Hematologic Malignancies
Recent EU Clinical Trials:A Phase II, Single Arm, Single Agent, Multicentre, Adaptive 2-Stage Study to Evaluate the Efficacy, Safety and Pharmacokinetics of AZD4877 Administered Weekly in Patients with Recurrent Advanced Urothelial Cancer

Technology Process of Azd-4877

There total 2 articles about Azd-4877 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: