2-BROMOMETHYL-6-METHOXYISOINDOLINONE

Base Information

Chemical Name:2-BROMOMETHYL-6-METHOXYISOINDOLINONE
CAS No.:944718-10-9
Molecular Formula:C₁₀H₁₀BrNO₂
Molecular Weight:256.099
Hs Code.:2933790090
Mol file:944718-10-9.mol

Synonyms:2-BROMOMETHYL-6-METHOXYISOINDOLINONE;2-Bromomethyl-6-methoxy-2,3-dihydro-isoindol-1-one;2-(BroMoMethyl)-6-Methoxyisoindolin-1-one

Suppliers and Price of 2-BROMOMETHYL-6-METHOXYISOINDOLINONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(Bromomethyl)-6-methoxyisoindolin-1-one 97%
1g
$ 608.00

Chemenu
2-(Bromomethyl)-6-methoxyisoindolin-1-one 95%+
1g
$ 574.00

American Custom Chemicals Corporation
2-BROMOMETHYL-6-METHOXY-2,3-DIHYDRO-ISOINDOL-1-ONE 95.00%
1G
$ 1074.50

Alichem
2-(Bromomethyl)-6-methoxyisoindolin-1-one
1g
$ 544.50

Total 6 raw suppliers

Chemical Property of 2-BROMOMETHYL-6-METHOXYISOINDOLINONE

Chemical Property:

Vapor Pressure:2.35E-06mmHg at 25°C
Boiling Point:392.1°C at 760 mmHg
Flash Point:190.9°C
PSA：29.54000
Density:1.558g/cm³
LogP:1.94130
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-(Bromomethyl)-6-methoxyisoindolin-1-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-BROMOMETHYL-6-METHOXYISOINDOLINONE

There total 5 articles about 2-BROMOMETHYL-6-METHOXYISOINDOLINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 944718-09-6
2,2-Dimethyl-propionic acid 6-methoxy-1-oxo-1,3-dihydro-isoindol-2-ylmethyl ester

: 944718-10-9
2-Bromomethyl-6-methoxy-2,3-dihydro-isoindol-1-one

Guidance literature:: With trimethylsilyl bromide; In dichloromethane;
DOI:10.1016/j.bmcl.2010.10.081

Reference yield:

: 73502-03-1
methyl 5-methoxy-2-methyl-benzoate

: 944718-10-9
2-Bromomethyl-6-methoxy-2,3-dihydro-isoindol-1-one

Guidance literature:: Multi-step reaction with 4 steps

1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Reflux

2: ammonia / methanol / 60 °C / Sealed tube

3: sodium t-butanolate; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / tetrahydrofuran / 5 h

4: trimethylsilyl bromide / dichloromethane / 2.5 h / 20 °C / Cooling with ice

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; N-Bromosuccinimide; trimethylsilyl bromide; ammonia; sodium t-butanolate; dibenzoyl peroxide; In tetrahydrofuran; methanol; tetrachloromethane; dichloromethane;

Reference yield:

: 788081-99-2
methyl 2-(bromomethyl)-5-methoxy-benzoate

: 944718-10-9
2-Bromomethyl-6-methoxy-2,3-dihydro-isoindol-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: ammonia / methanol / 60 °C / Sealed tube

2: sodium t-butanolate; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / tetrahydrofuran / 5 h

3: trimethylsilyl bromide / dichloromethane / 2.5 h / 20 °C / Cooling with ice

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; trimethylsilyl bromide; ammonia; sodium t-butanolate; In tetrahydrofuran; methanol; dichloromethane;