N-(2-nitrophenyl)pyrazine-2-carboxamide

Base Information

Chemical Name:N-(2-nitrophenyl)pyrazine-2-carboxamide
CAS No.:2604-91-3
Molecular Formula:C11H8N4O3
Molecular Weight:244.21
Hs Code.:
Nikkaji Number:J2.566.573B

Synonyms:N-(2-nitrophenyl)pyrazine-2-carboxamide;2604-91-3;Cambridge id 5528055;Oprea1_277098;STK431944;N-(2-nitrophenyl)pyrazinecarboxamide?;AKOS003237277;N-(2-Nitrophenyl)-2-pyrazinecarboxamide;CS-0328205;S11888;SR-01000211476;SR-01000211476-1

Suppliers and Price of N-(2-nitrophenyl)pyrazine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
N-(2-Nitrophenyl)pyrazine-2-carboxamide 95%+
1g
$ 904.00

Total 7 raw suppliers

Chemical Property of N-(2-nitrophenyl)pyrazine-2-carboxamide

Chemical Property:

PSA：100.70000
LogP:2.23330
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:244.05964013
Heavy Atom Count:18
Complexity:318

Purity/Quality:

99% ^*data from raw suppliers

N-(2-Nitrophenyl)pyrazine-2-carboxamide 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NC(=O)C2=NC=CN=C2)[N+](=O)[O-]

Technology Process of N-(2-nitrophenyl)pyrazine-2-carboxamide

There total 3 articles about N-(2-nitrophenyl)pyrazine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 98-97-5
2-pyrazylcarboxylic acid

: 88-74-4
2-nitro-aniline

: 2604-91-3
N-(2-nitrophenyl)pyrazine-2-carboxamide

Guidance literature:: With dmap; 2,4,6-trichlorobenzoyl chloride; triethylamine; In tetrahydrofuran; for 23h; Reflux;
DOI:10.1007/s00044-020-02626-0

Reference yield:

: 98-97-5
2-pyrazylcarboxylic acid

: 2604-91-3
N-(2-nitrophenyl)pyrazine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C / Inert atmosphere

2: tetrahydrofuran / 20 °C

With thionyl chloride; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;
DOI:10.1002/jhet.921