(6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid

Base Information

Chemical Name:(6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid
CAS No.:1190392-22-3
Molecular Formula:C8H8N2O3
Molecular Weight:180.163
Hs Code.:
Mol file:1190392-22-3.mol

Synonyms:(6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid;(S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylicacid

Suppliers and Price of (6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
(6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyrimidine-6-carboxylicacid 97.00%
25G
$ 4470.00

AccelPharmtech
(6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyrimidine-6-carboxylicacid 97.00%
5G
$ 2390.00

Total 18 raw suppliers

Chemical Property of (6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid

Chemical Property:

Boiling Point:392.2±44.0 °C(Predicted)
PKA:2.72±0.20(Predicted)
PSA：72.19000
Density:1.61±0.1 g/cm3(Predicted)
LogP:-0.18480

Purity/Quality:

99%, ^*data from raw suppliers

(6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyrimidine-6-carboxylicacid 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid

There total 3 articles about (6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1190392-23-4
methyl [6(S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-α]]pyrimidine-6-carboxylate

: 1190392-22-3
(6S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-α]pyrimidine-6-carboxylic acid

Guidance literature:: methyl [6(S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-α]]pyrimidine-6-carboxylate; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;

Reference yield:

: 173142-47-7
methyl (2S)-5-methoxy-3,4-dihydro-2H-pyrrole-2-carboxylate

: 1190392-22-3
(6S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-α]pyrimidine-6-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 110 °C

2: water; lithium hydroxide / tetrahydrofuran; methanol / 1 h / 20 °C

With water; lithium hydroxide; In tetrahydrofuran; methanol;

Reference yield:

: 1190709-67-1
methyl (7S)-9-oxo-3,8-diazatetracyclo[9.2.1.0(2,10).0(4,8)]tetradeca-3,12-diene-7-carboxylate

: 1190392-22-3
(6S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-α]pyrimidine-6-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 0.75 h / 150 °C

2: water; lithium hydroxide / tetrahydrofuran; methanol / 1 h / 20 °C

With water; lithium hydroxide; In tetrahydrofuran; methanol;