173142-47-7Relevant articles and documents
RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF
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Paragraph 0085-0086, (2021/01/28)
The present invention discloses a receptor inhibitor of formula (I), a pharmaceutical composition comprising the same and the use thereof.
A process for producing an intermediate agonist GRK 3
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Paragraph 0144; 0156-0160, (2016/10/10)
The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
Synthesis of an azabicycloalkane amino acid scaffold as potential rigid dipeptide mimetic
Millet, Régis,Domarkas, Juozas,Rombaux, Pauline,Rigo, Beno?t,Houssin, Raymond,Hénichart, Jean-Pierre
, p. 5087 - 5088 (2007/10/03)
Short syntheses are presented of the pseudo-dipeptide (3S,6S)-6-[(benzyloxy)carbonyl]amino-5-oxo-1,2,3,5,6,7-hexahydro-3- indolizinecarboxylic acid (1a) and of its (3S,6R) diastereoisomer (1b). The key step involves adding vinylogous β-enaminoester derived from pyroglutamic acid on an acrylate derivative. The 6,5-fused bicyclic lactam obtained may be viewed as a conformationally restricted Ala-Pro mimetic.