1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID

Base Information

Chemical Name:1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID
CAS No.:54802-31-2
Molecular Formula:C₁₅H₂₀O₄
Molecular Weight:264.321
Hs Code.:
Mol file:54802-31-2.mol

Synonyms:1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID;1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANE-1-CARBOXYLIC ACID;AKOS BBV-005043

Suppliers and Price of 1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID 98.00%
1G
$ 983.52

AK Scientific
1-(3,4-Dimethoxyphenyl)cyclohexane-1-carboxylicacid
250mg
$ 340.00

Total 6 raw suppliers

Chemical Property of 1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID

Chemical Property:

PSA：55.76000
LogP:2.99030

Purity/Quality:

97% ^*data from raw suppliers

1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID

There total 5 articles about 1-(3,4-DIMETHOXYPHENYL)CYCLOHEXANECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 54802-31-2
1-(3,4-Dimethoxy-phenyl)-cyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C

1.2: 20 - 60 °C

2.1: sodium hydroxide / water / 24 h / Reflux

With sodium hydride; sodium hydroxide; In tetrahydrofuran; water;
DOI:10.1021/acs.jmedchem.9b00751

Reference yield:

: 54802-32-3
1-(3,4-dimethoxyphenyl)cyclohexanecarbonitrile

: 54802-31-2
1-(3,4-Dimethoxy-phenyl)-cyclohexanecarboxylic acid

Guidance literature:: With sodium hydroxide; In water; for 24h; Reflux;
DOI:10.1021/acs.jmedchem.9b00751

Reference yield:

: 15964-79-1
methyl (3,4-dimethoxyphenyl)acetate

: 54802-31-2
1-(3,4-Dimethoxy-phenyl)-cyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C

1.2: 1,5-halopentane / 18.17 h / 0 - 50 °C

2.1: sodium hydroxide / methanol; water / 3 h / Reflux

With sodium hydride; sodium hydroxide; In tetrahydrofuran; methanol; water; mineral oil;
DOI:10.1021/acs.jmedchem.0c00230