93-17-4Relevant articles and documents
Total synthesis of isopavine and intermediates for the preparation of substituted amitriptyline analogues: Facile routes to substituted dibenzocyclooctatrienes and dibenzocycloheptatrienes
Jung,Miller
, p. 1984 - 1992 (1981)
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Nickel-Catalyzed Photodehalogenation of Aryl Bromides
Higginson, Bradley,Sanjosé-Orduna, Jesus,Gu, Yiting,Martin, Ruben
supporting information, p. 1633 - 1636 (2021/04/23)
Herein, we describe a Ni-catalyzed photodehalogenation of aryl bromides under visible-light irradiation that utilizes tetrahydrofuran as hydrogen source. The protocol obviates the need for exogeneous amine reductants or photocatalysts and is characterized by its simplicity and broad scope, including challenging substrate combinations.
Production technology of 3,4-dimethoxy phenethylamine
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, (2016/10/08)
A production technology of 3,4-dimethoxyphenethylamine is disclosed, and characterized by using 3,4-dihydroxybenzyl chloride and dimethyl sulfate as raw materials; performing an etherification reaction to generate 3,4-dimethoxybenzyl chloride in the presence of sodium hydrate; performing an cyanation reaction on the 3,4-dimethoxybenzyl chloride and a cyanide compound to generate 3,4-dimethoxybenzyl cyanide; cooling the 3,4-dimethoxybenzyl cyanide in propanone for crystallization to obtain 3,4-dimethoxybenzyl cyanide crystals; subjecting 3,4-dimethoxybenzyl cyanide to catalytic ammoniation and hydrogenation in a solvent to generate 3,4-dimethoxyphenethylamine; and performing reduced-pressure distillation on the product obtained after ammoniation and hydrogenation to obtain an qualified product of 3,4-dimethoxyphenethylamine. The overall product yield is 86% or higher.