Ethyl 3,4,5-trimethoxyphenylacetate

Base Information

Chemical Name:Ethyl 3,4,5-trimethoxyphenylacetate
CAS No.:66162-60-5
Molecular Formula:C13H18O5
Molecular Weight:254.283
Hs Code.:2918990090
NSC Number:141200
DSSTox Substance ID:DTXSID30301118
Wikidata:Q82044707
Mol file:66162-60-5.mol

Synonyms:66162-60-5;Ethyl 3,4,5-trimethoxyphenylacetate;ethyl 2-(3,4,5-trimethoxyphenyl)acetate;Ethyl 3,4,5-trimethoxyphenyl acetate;NSC141200;SCHEMBL3457181;DTXSID30301118;MFCD04038963;AKOS005254582;NSC-141200;ETHYL-3,4,5-TRIMETHOXYPHENYLACETATE;(3,4,5-Trimethoxyphenyl)acetic acid ethyl ester;Benzeneacetic acid,3,4,5-trimethoxy-,ethyl ester

Suppliers and Price of Ethyl 3,4,5-trimethoxyphenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
(3,4,5-Trimethoxyphenyl)aceticacidethylester
5g
$ 1728.00

Rieke Metals
(3,4,5-Trimethoxyphenyl)aceticacidethylester
1g
$ 661.00

American Custom Chemicals Corporation
ETHYL 3,4,5-TRIMETHOXYPHENYL ACETATE 95.00%
5MG
$ 501.46

Total 11 raw suppliers

Chemical Property of Ethyl 3,4,5-trimethoxyphenylacetate

Chemical Property:

Boiling Point:333.9 °C at 760 mmHg
Flash Point:144.3 °C
PSA：53.99000
Density:1.101 g/cm³
LogP:1.81800
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:254.11542367
Heavy Atom Count:18
Complexity:242

Purity/Quality:

99% ^*data from raw suppliers

(3,4,5-Trimethoxyphenyl)aceticacidethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=CC(=C(C(=C1)OC)OC)OC

Technology Process of Ethyl 3,4,5-trimethoxyphenylacetate

There total 5 articles about Ethyl 3,4,5-trimethoxyphenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 64-17-5
ethanol

: 951-82-6
3,4,5-trimethoxyphenyl acetic acid

: 66162-60-5
(3,4,5-trimethoxyphenyl)acetic acid ethyl ester

Guidance literature:: With sulfuric acid; In toluene; Reflux;

Reference yield: 74.0%

: 951-82-6
3,4,5-trimethoxyphenyl acetic acid

: 66162-60-5
(3,4,5-trimethoxyphenyl)acetic acid ethyl ester

Guidance literature:: DOI:10.1002/jhet.5570280507

Reference yield:

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 66162-60-5
(3,4,5-trimethoxyphenyl)acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2NMe₃>OH / tetrahydrofuran; methanol / 12 h / Heating

2: HCl / 1.5 h / Heating

With hydrogenchloride; N-benzyl-trimethylammonium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1246/bcsj.52.2013