3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol

Base Information

Chemical Name:3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol
CAS No.:95711-07-2
Molecular Formula:C12H7ClF3NO2
Molecular Weight:289.64
Hs Code.:2933399090
DSSTox Substance ID:DTXSID20382395
Wikidata:Q82173737
ChEMBL ID:CHEMBL1335531
Mol file:95711-07-2.mol

Synonyms:95711-07-2;3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol;3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-oxy}benzenol;3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenol;3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenol;3-([3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy)benzenol;3-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}benzenol;Bionet2_000207;MLS000755420;CHEMBL1335531;SCHEMBL11456016;DTXSID20382395;HMS1364J09;HMS2623J12;VDA71107;MFCD00172750;AKOS005069839;SMR000337805;CS-0315349;MLS000755420-02;1F-058;J-510375;2-(3-hydroxyphenoxy)-3-chloro-5-trifluoromethyl pyridine;3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenol;3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy} benzenol

Suppliers and Price of 3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol
500 mg
$ 71.00

Matrix Scientific
3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-oxy}benzenol >95%
5g
$ 698.00

Matrix Scientific
3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-oxy}benzenol >95%
1g
$ 304.00

Matrix Scientific
3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-oxy}benzenol >95%
500mg
$ 244.00

Crysdot
3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenol 95+%
5g
$ 847.00

Chemenu
3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenol 95%
5g
$ 799.00

AK Scientific
3-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-oxy}benzenol
500mg
$ 204.00

Total 5 raw suppliers

Chemical Property of 3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol

Chemical Property:

Melting Point:100-102°C
PSA：42.35000
LogP:4.25170
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:289.0117406
Heavy Atom Count:19
Complexity:303

Purity/Quality:

98%min ^*data from raw suppliers

3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl)O

Technology Process of 3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol

There total 1 articles about 3-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 69045-84-7
2,3-dichloro-5-trifluoromethylpyridine

: 108-46-3
recorcinol

: 95711-07-2
3-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenol

Guidance literature:: With potassium hydroxide; dimethyl sulfoxide; at 100 ℃; for 3h;
DOI:10.1016/j.jfluchem.2006.07.011

Reference yield: 89.0%

: 95711-07-2
3-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenol

: 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl sulfurofluoridate

Guidance literature:: With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 18h; Sealed tube;
DOI:10.1002/anie.201802647

Reference yield: 66.0%

: 95711-07-2
3-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenol

: 103669-71-2
(Z)-methyl 2-(bromomethyl)-3-phenylacrylate

: 950994-18-0
methyl 2-((3-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)phenoxy)(phenyl)methyl)acrylate

Guidance literature:: (Z)-methyl 2-(bromomethyl)-3-phenylacrylate; With triethylamine; In dichloromethane; at 20 ℃; for 0.25h;

3-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenol; In dichloromethane; at 20 ℃; for 8h; Further stages.;
DOI:10.1016/j.jfluchem.2006.07.011