4-Deschloro-4-(2-furanylMethyl)aMino FuroseMide

Base Information

• Chemical Name: 4-Deschloro-4-(2-furanylMethyl)aMino FuroseMide
• CAS No.: 5046-19-5
• Molecular Formula: C17H17N3O6S
• Molecular Weight: 391.39838
• Mol file: 5046-19-5.mol

Synonyms:4-Deschloro-4-(2-furanylMethyl)aMino FuroseMide;2,4-Bis(furfurylaMino)-5-sulfaMoylbenzoic Acid;5-(AMinosulfonyl)-2,4-bis[(2-furanylMethyl)aMino]benzoic Acid;FuroseMide EP IMpurity D;Furosemide Impurity D

Chemical Property of 4-Deschloro-4-(2-furanylMethyl)aMino FuroseMide

Chemical Property:

• Melting Point: 217℃ (decomposition) (ethanol )
• Boiling Point: 643.4±65.0 °C(Predicted)
• PKA: 3.75±0.36(Predicted)
• PSA: 156.18000
• Density: 1.524±0.06 g/cm3(Predicted)
• LogP: 4.36950
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

99.90% ^*data from raw suppliers

4-Deschloro-4-(2-furanylmethyl)aminoFurosemide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Deschloro-4-(2-furanylmethyl)amino Furosemide (Furosemide EP Impurity D) is a Furosemide (F865000) Impurity. A Furosemide (F865000) Impurity.

Technology Process of 4-Deschloro-4-(2-furanylMethyl)aMino FuroseMide

There total 2 articles about 4-Deschloro-4-(2-furanylMethyl)aMino FuroseMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-4-furfurylamino-5-sulfamoyl-benzoic acid (4818-59-1) + furan-2-ylmethanamine (617-89-0) → 2,4-bis-furfurylamino-5-sulfamoyl-benzoic acid (5046-19-5)

Guidance literature:

2-chloro-4-furfurylamino-5-sulfamoyl-benzoic acid; furan-2-ylmethanamine; at 125 ℃; for 72h;

With hydrogenchloride; In water; ethyl acetate;

Reference yield:

→ 2,4-bis-furfurylamino-5-sulfamoyl-benzoic acid (5046-19-5)

Guidance literature:

entspr.Ethylester, 2n-NaOH, kurz auf 60-70grad;

upstream raw materials:

2-chloro-4-furfurylamino-5-sulfamoyl-benzoic acid

furan-2-ylmethanamine

Refernces