DL-B-HYDROXYMYRISTIC ACID

Base Information

• Chemical Name: DL-B-HYDROXYMYRISTIC ACID
• CAS No.: 3422-31-9
• Molecular Formula: C₁₄H₂₈O₃
• Molecular Weight: 244.375
• Mol file: 3422-31-9.mol

Synonyms:DL-B-HYDROXYMYRISTIC ACID;dl-β-hydroxymyristic acid

Chemical Property of DL-B-HYDROXYMYRISTIC ACID

Chemical Property:

• PSA: 57.53000
• LogP: 3.74290
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

DL-β-Hydroxymyristic acid ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DL-B-HYDROXYMYRISTIC ACID

There total 80 articles about DL-B-HYDROXYMYRISTIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 3-oxotetradecanoate (22348-97-6) → (R)-3-hydroxytetradecanoic acid (28715-21-1,3422-31-9)

Guidance literature:

methyl 3-oxotetradecanoate; With hydrogen; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; ruthenium trichloride; In methanol; at 40 - 50 ℃; for 20h; under 3361.46 Torr;

With lithium hydroxide; In tetrahydrofuran; water;

DOI:10.1016/j.tetlet.2006.01.137

Reference yield: 98.0%

methyl (R)-3-hydroxytetradecanoate (76062-97-0) → (R)-3-hydroxytetradecanoic acid (28715-21-1,3422-31-9)

Guidance literature:

With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 2h;

Reference yield: 95.0%

(R)-1-cyanotridecan-2-ol (259799-90-1) → (R)-3-hydroxytetradecanoic acid (28715-21-1,3422-31-9)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 100 ℃; for 12h;

upstream raw materials:

methyl 3-oxotetradecanoate

Dodecanal

ethyl bromoacetate

cycl-isopropylidene malonate

Downstream raw materials:

(3R)-3-hydroxytetradecanoic acid phenacyl ester

Refernces

• 1、 Di Lorenzo, Flaviana,Speciale, Immacolata,Silipo, Alba,Alías-Villegas, Cynthia,Acosta-Jurado, Sebastián,Rodríguez-Carvajal, Miguel-ángel,Dardanelli, Marta S.,Palmigiano, Angelo,Garozzo, Domenico,Ruiz-Sainz, José-Enrique,Molinaro, Antonio,Vinardell, José-María. "Structure of the unusual Sinorhizobium fredii HH103 lipopolysaccharide and its role in symbiosis". . p. 10969 - 10987. Retrieved 2021/01/07.
• 2、 Onoda, Hiroki,Shoji, Osami,Suzuki, Kazuto,Sugimoto, Hiroshi,Shiro, Yoshitsugu,Watanabe, Yoshihito. "α-Oxidative decarboxylation of fatty acids catalysed by cytochrome P450 peroxygenases yielding shorter-alkyl-chain fatty acids". . p. 434 - 442. Retrieved 2018/02/07.