(S)-2-Amino-2-(4-bromophenyl)acetic acid

Base Information

Chemical Name:(S)-2-Amino-2-(4-bromophenyl)acetic acid
CAS No.:848188-26-1
Molecular Formula:C8H8BrNO2
Molecular Weight:230.061
Hs Code.:2922499990
DSSTox Substance ID:DTXSID50426155
Mol file:848188-26-1.mol

Synonyms:(S)-2-Amino-2-(4-bromophenyl)acetic acid;848188-26-1;(2S)-2-amino-2-(4-bromophenyl)acetic acid;(S)-2-Amino-2-(4-bromophenyl)aceticacid;DTXSID50426155;MFCD07371735;AKOS015927186;CS-0143792;N10975;(S)-2-Amino-2-(4-bromophenyl)acetic acid (H-L-Phg(4-Br)-OH)

Suppliers and Price of (S)-2-Amino-2-(4-bromophenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-Amino-2-(4-bromophenyl)aceticacid 95+%
5g
$ 432.00

American Custom Chemicals Corporation
L-4-BROMOPHENYLGLYCINE 95.00%
0.5G
$ 600.00

American Custom Chemicals Corporation
L-4-BROMOPHENYLGLYCINE 95.00%
5MG
$ 497.95

Alichem
(S)-2-Amino-2-(4-bromophenyl)aceticacid
5g
$ 434.52

Activate Scientific
(S)-2-Amino-2-(4-bromophenyl)acetic acid 95+% ee
1 g
$ 223.00

Activate Scientific
(S)-2-Amino-2-(4-bromophenyl)acetic acid 95+% ee
5 g
$ 640.00

Acrotein
(S)-2-Amino-2-(4-bromophenyl)aceticacid 97%
0.5g
$ 110.00

ACHEMBLOCK
(S)-2-Amino-2-(4-bromophenyl)aceticacid 98%
5G
$ 630.00

ACHEMBLOCK
(S)-2-Amino-2-(4-bromophenyl)aceticacid 98%
1G
$ 220.00

Total 16 raw suppliers

Chemical Property of (S)-2-Amino-2-(4-bromophenyl)acetic acid

Chemical Property:

Boiling Point:363.2±32.0 °C(Predicted)
PKA:1.81±0.10(Predicted)
PSA：63.32000
Density:1.673±0.06 g/cm3(Predicted)
LogP:2.23380
Storage Temp.:2-8°C
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:228.97384
Heavy Atom Count:12
Complexity:166

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-Amino-2-(4-bromophenyl)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C(=O)O)N)Br
Isomeric SMILES:C1=CC(=CC=C1[C@@H](C(=O)O)N)Br

Technology Process of (S)-2-Amino-2-(4-bromophenyl)acetic acid

There total 1 articles about (S)-2-Amino-2-(4-bromophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-66-3,8013-54-5
chloroform

: 1122-91-4
4-bromo-benzaldehyde

: 848188-26-1
(S)-Amino-(4-bromo-phenyl)-acetic acid

: 71079-03-3,119397-06-7,129592-99-0
(R)-4-bromophenylglycine

Guidance literature:: With potassium hydroxide; ammonia; (+)-(1S,2R)-N-hexadecyl-N-methylephedrinium bromide; lithium chloride; In ethanol; Product distribution; 5 deg C, 4 h, RT, overnight; asymmetric induction;

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 848188-26-1
(S)-Amino-(4-bromo-phenyl)-acetic acid

: 1228570-47-5
C₁₃H₁₆BrNO₄

Guidance literature:: With potassium carbonate; In tetrahydrofuran; water;
DOI:10.1021/acs.jmedchem.8b01144

Reference yield:

: 848188-26-1
(S)-Amino-(4-bromo-phenyl)-acetic acid

: C₂₃H₂₆BrN₃O₃

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / water; tetrahydrofuran

2: N-ethyl-N,N-diisopropylamine; isobutyl chloroformate / tetrahydrofuran / -20 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; isobutyl chloroformate; In tetrahydrofuran; water;
DOI:10.1021/acs.jmedchem.8b01144