4-Chlorophenyl cyclohexyl ketone

Base Information

Chemical Name:4-Chlorophenyl cyclohexyl ketone
CAS No.:3277-80-3
Molecular Formula:C13H15ClO
Molecular Weight:222.715
Hs Code.:2914700090
DSSTox Substance ID:DTXSID40468887
Nikkaji Number:J283.906G
Wikidata:Q82296356
Mol file:3277-80-3.mol

Synonyms:4-CHLOROPHENYL CYCLOHEXYL KETONE;3277-80-3;(4-chlorophenyl)-cyclohexylmethanone;MFCD00454416;SCHEMBL196518;DTXSID40468887;PTYKBHNDBXPYKO-UHFFFAOYSA-N;(4-Chlorophenyl)cyclohexylmethanone;4-(cyclohexylcarbonyl)-chlorobenzene;4-CHLOROPHENYLCYCLOHEXYLKETONE;AKOS000346043

Suppliers and Price of 4-Chlorophenyl cyclohexyl ketone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
4-CHLOROPHENYLCYCLOHEXYLKETONE
5g
$ 1943.00

Rieke Metals
4-Chlorophenylcyclohexylketone 97%
5g
$ 1514.00

Rieke Metals
4-CHLOROPHENYLCYCLOHEXYLKETONE
1g
$ 809.00

Rieke Metals
4-Chlorophenylcyclohexylketone 97%
2g
$ 731.00

Rieke Metals
4-Chlorophenylcyclohexylketone 97%
1g
$ 417.00

Matrix Scientific
4-Chlorophenyl cyclohexyl ketone 97%
1g
$ 437.00

Matrix Scientific
4-Chlorophenyl cyclohexyl ketone 97%
2g
$ 726.00

Matrix Scientific
4-Chlorophenyl cyclohexyl ketone 97%
5g
$ 1412.00

Crysdot
4-Chlorophenylcyclohexylketone 95+%
5g
$ 1401.00

Crysdot
4-Chlorophenylcyclohexylketone 95+%
1g
$ 433.00

Total 5 raw suppliers

Chemical Property of 4-Chlorophenyl cyclohexyl ketone

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:61.5-62.5 °C
Boiling Point:337.38°C at 760 mmHg
Flash Point:186.552°C
PSA：17.07000
Density:1.14g/cm³
LogP:4.10300
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:222.0811428
Heavy Atom Count:15
Complexity:213

Purity/Quality:

97% ^*data from raw suppliers

4-CHLOROPHENYLCYCLOHEXYLKETONE ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)C(=O)C2=CC=C(C=C2)Cl

Technology Process of 4-Chlorophenyl cyclohexyl ketone

There total 35 articles about 4-Chlorophenyl cyclohexyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1267278-69-2
1-(4-chlorophenyl)cyclohexane-1-carbaldehyde

: 3277-80-3
(4-chlorophenyl)(cyclohexyl)methanone

Guidance literature:: With ferric(III) bromide; In toluene; at 130 ℃; for 14h; chemoselective reaction; Sealed tube; Schlenk technique; Inert atmosphere;
DOI:10.1021/ja4068707

Reference yield: 89.0%

: 931-51-1
cyclohexylmagnesiumchloride

: 74-11-3
para-chlorobenzoic acid

: 3277-80-3
(4-chlorophenyl)(cyclohexyl)methanone

Guidance literature:: para-chlorobenzoic acid; With tert-butylmagnesium chloride; In tetrahydrofuran; toluene; at 0 ℃; for 0.25h; Inert atmosphere;

cyclohexylmagnesiumchloride; With diisopropylaminomagnesium chloride lithium chloride; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 7.25h; Inert atmosphere; Sonication;
DOI:10.1021/acs.orglett.9b02899

Reference yield: 87.0%

: 106-39-8
bromochlorobenzene

: 2043-61-0
cyclohexanecarbaldehyde

: 3277-80-3
(4-chlorophenyl)(cyclohexyl)methanone

Guidance literature:: bromochlorobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

cyclohexanecarbaldehyde; In tetrahydrofuran; hexane; at -78 ℃; for 2h;

With iodine; potassium carbonate; In tert-butyl alcohol; for 8h; Reflux;
DOI:10.1016/j.tet.2011.12.023