3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE)

Base Information

• Chemical Name: 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE)
• CAS No.: 689250-53-1
• Molecular Formula: C11H9FN2O
• Molecular Weight: 204.204
• Hs Code.: 2933199090
• Mol file: 689250-53-1.mol

Synonyms:3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE)

Chemical Property of 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE)

Chemical Property:

• Vapor Pressure: 3.66E-05mmHg at 25°C
• Boiling Point: 353.1°C at 760 mmHg
• Flash Point: 167.4°C
• PSA: 34.89000
• Density: 1.21g/cm³
• LogP: 2.03870

Purity/Quality:

97% ^*data from raw suppliers

3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE)

There total 5 articles about 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.6%

3-(4-fluorophenyl)-1H-pyrazole-4-carbaldehyde (306936-57-2) + methyl iodide (74-88-4) → 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde (689250-53-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 - 60 ℃;

DOI:10.1016/j.ejmech.2017.03.030

Reference yield:

C11H11FN2O (689250-51-9) + C11H11FN2O (1176628-01-5) → 5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde (689250-52-0) + 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde (689250-53-1)

Guidance literature:

With manganese(IV) oxide; In tetrahydrofuran; at 20 ℃; for 14h;

Reference yield:

3-(4-fluorophenyl)-1H-pyrazole-4-carbaldehyde (306936-57-2) + methyl iodide (74-88-4) → 5-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde (689250-52-0) + 3-(4-fluorophenyl)-1-methyl-1H-pyrazole-4-carbaldehyde (689250-53-1)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃;

DOI:10.1016/j.bmcl.2008.08.058

upstream raw materials:

C₁₁H₁₁FN₂O

C₁₁H₁₁FN₂O

3-(4-fluorophenyl)-1H-pyrazole-4-carbaldehyde

methyl iodide