UM729

Base Information

Chemical Name:UM729
CAS No.:1448723-60-1
Molecular Formula:C20H25N5O2
Molecular Weight:367.44
Hs Code.:
Mol file:1448723-60-1.mol

Synonyms:UM729;C07;methyl 4-(3-(piperidin-1-yl)propylamino)-9H-pyrimido[4,5-b]indole-7-carboxylate;4-[[3-(1-Piperidinyl)propyl]amino]-9H-pyrimido[4,5-b]indole-7-carboxylic acid methyl ester

Suppliers and Price of UM729

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
UM729 >98%
250 mg
$ 1100.00

DC Chemicals
UM729 >98%
1 g
$ 2300.00

DC Chemicals
UM729 >98%
100 mg
$ 600.00

Crysdot
UM729 98+%
100mg
$ 571.00

Crysdot
UM729 98+%
50mg
$ 466.00

Crysdot
UM729 98+%
10mg
$ 186.00

Crysdot
UM729 98+%
5mg
$ 112.00

Biorbyt Ltd
UM729 >98%
1 g
$ 3432.30

Biorbyt Ltd
UM729 >98%
250 mg
$ 1654.10

Biorbyt Ltd
UM729 >98%
100 mg
$ 912.90

Total 12 raw suppliers

Chemical Property of UM729

Chemical Property:

PSA：83.14000
LogP:3.19650

Purity/Quality:

97% ^*data from raw suppliers

UM729 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of UM729

There total 5 articles about UM729 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.1%

: 3529-08-6
1-(3-aminopropyl)piperidine

: 1096471-98-5
methyl 4-chloro-9H-pyrimido[4,5-b]indole-7-carboxylate

: 1448723-60-1
methyl 4-((3-(piperidin-1-yl)propyl)amino)-9H-pyrimido[4,5-b]indole-7-carboxylate

Guidance literature:: With triethylamine; In methanol; at 140 ℃; for 0.25h; Microwave irradiation;

Reference yield:

: 329-59-9
4-fluoro-3-nitro-benzoic acid methyl ester

: 1448723-60-1
methyl 4-((3-(piperidin-1-yl)propyl)amino)-9H-pyrimido[4,5-b]indole-7-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.25 h / 0 °C

1.2: 3.5 h / 0 - 20 °C

2.1: zinc; acetic acid / 15.58 h / 100 °C

3.1: formamide / 12 h / 20 - 165 °C

4.1: trichlorophosphate / 16 h / 90 °C

5.1: triethylamine / methanol / 0.25 h / 140 °C / Microwave irradiation

With sodium hydride; acetic acid; triethylamine; zinc; trichlorophosphate; In methanol; formamide; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 105600-18-8
methyl 4-(1-cyano-2-ethoxy-2-oxoethyl)-3-nitrobenzoate

: 1448723-60-1
methyl 4-((3-(piperidin-1-yl)propyl)amino)-9H-pyrimido[4,5-b]indole-7-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: zinc; acetic acid / 15.58 h / 100 °C

2: formamide / 12 h / 20 - 165 °C

3: trichlorophosphate / 16 h / 90 °C

4: triethylamine / methanol / 0.25 h / 140 °C / Microwave irradiation

With acetic acid; triethylamine; zinc; trichlorophosphate; In methanol; formamide;