6H-Dibenz[b,d]azepin-6-one, 7-aMino-5,7-dihydro-5-Methyl- (hydrochloride)(1:1)

Base Information

• Chemical Name: 6H-Dibenz[b,d]azepin-6-one, 7-aMino-5,7-dihydro-5-Methyl- (hydrochloride)(1:1)
• CAS No.: 209984-32-7
• Molecular Weight: 274.7454
• Mol file: 209984-32-7.mol

Synonyms:6H-Dibenz[b,d]azepin-6-one, 7-aMino-5,7-dihydro-5-Methyl- (hydrochloride)(1:1)

Chemical Property of 6H-Dibenz[b,d]azepin-6-one, 7-aMino-5,7-dihydro-5-Methyl- (hydrochloride)(1:1)

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

7-Amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-onehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6H-Dibenz[b,d]azepin-6-one, 7-aMino-5,7-dihydro-5-Methyl- (hydrochloride)(1:1)

There total 2 articles about 6H-Dibenz[b,d]azepin-6-one, 7-aMino-5,7-dihydro-5-Methyl- (hydrochloride)(1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(S,S)-7-amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one (2S,3S)-2,3-bis(4-methylbenzoyloxy)succinate → (S,S)-7-amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one hydrochloride (209984-55-4,209984-32-7)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 50 ℃;

DOI:10.1016/j.tetasy.2009.04.016

Reference yield:

7-amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one hydrochloride (213024-76-1) → (S,S)-7-amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one hydrochloride (209984-55-4,209984-32-7)

Guidance literature:

7-amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one hydrochloride; With (2S,3S)-di-4-toluoyltartaric acid; In methanol; at 20 ℃; for 8 - 72h;

With sodium hydrogencarbonate; In ethyl acetate; pH=9 - 10;

With hydrogenchloride; In methanol;

Reference yield:

7-amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one hydrochloride (209984-32-7) + (1S)-(+)-menthyl chloroformate → C27H34N2O2 + C27H34N2O2

Guidance literature:

With triethylamine; In diethyl ether; at 20 ℃; for 2h;

DOI:10.3390/molecules180910747

upstream raw materials:

7-amino-5-methyl-5H-dibenzo[b,d]azepin-6(7H)-one hydrochloride

Downstream raw materials:

(S)-5-(N-Boc-L-alaninyl)amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

(R)-5-(N-Boc-L-alaninyl)amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one