N-(5α-Androst-2-en-3-yl)-N-ethylacetamide

Base Information

• Chemical Name: N-(5α-Androst-2-en-3-yl)-N-ethylacetamide
• CAS No.: 4642-51-7
• Molecular Weight: 343.55
• Mol file: 4642-51-7.mol

Synonyms:N-(5α-Androst-2-en-3-yl)-N-ethylacetamide

Chemical Property of N-(5α-Androst-2-en-3-yl)-N-ethylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(5α-Androst-2-en-3-yl)-N-ethylacetamide

There total 3 articles about N-(5α-Androst-2-en-3-yl)-N-ethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

androstan-3-one (1224-95-9,118371-41-8) → 3--5α-androst-2-en (4642-51-7)

Guidance literature:

Multi-step reaction with 3 steps

1: TsOH

2: K₂CO₃

3: Raney-Ni / benzene

With potassium carbonate; toluene-4-sulfonic acid; nickel; In benzene;

DOI:10.1039/jr9650006253

Reference yield:

5α-Androstan-3-spiro-2'-thiazolidin (4642-50-6) → 3--5α-androst-2-en (4642-51-7)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃

2: Raney-Ni / benzene

With potassium carbonate; nickel; In benzene;

DOI:10.1039/jr9650006253

Reference yield:

3'-acetyl-(3ξN,5α)-spiro[androstane-3,2'-thiazolidine] (4678-96-0) → 3--5α-androst-2-en (4642-51-7)

Guidance literature:

nickel; In benzene;

DOI:10.1039/jr9650006253

upstream raw materials:

3'-acetyl-(3ξN,5α)-spiro[androstane-3,2'-thiazolidine]

androstan-3-one

5α-Androstan-3-spiro-2'-thiazolidin