2-[4-(Tert-butoxycarbonyl)piperazine-1-YL]phenylboronic acid

Base Information

Chemical Name:2-[4-(Tert-butoxycarbonyl)piperazine-1-YL]phenylboronic acid
CAS No.:915770-01-3
Molecular Formula:C₁₅H₂₃BN₂O₄
Molecular Weight:306.17
Hs Code.:
DSSTox Substance ID:DTXSID20681754
Wikidata:Q82605896

Synonyms:915770-01-3;2-[4-(TERT-BUTOXYCARBONYL)PIPERAZINE-1-YL]PHENYLBORONIC ACID;[2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]phenyl]boronic acid;2-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenylboronic acid;(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)phenyl)boronic acid;{2-[4-(tert-Butoxycarbonyl)piperazin-1-yl]phenyl}boronic acid;SCHEMBL4133762;DTXSID20681754;AMY32293;MFCD09753310;AKOS015893114;AS-40327;2-(4-Boc-piperazin-1-yl)phenylboronic acid;CS-0178774

Suppliers and Price of 2-[4-(Tert-butoxycarbonyl)piperazine-1-YL]phenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 2-[4-(Tert-butoxycarbonyl)piperazine-1-YL]phenylboronic acid

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:306.1750874
Heavy Atom Count:22
Complexity:378

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC=CC=C1N2CCN(CC2)C(=O)OC(C)(C)C)(O)O

Technology Process of 2-[4-(Tert-butoxycarbonyl)piperazine-1-YL]phenylboronic acid

There total 1 articles about 2-[4-(Tert-butoxycarbonyl)piperazine-1-YL]phenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 494773-35-2
4-(2-bromophenyl)piperazine-1-carboxylic acid tert-butyl ester

: 915770-01-3
2-[(4-tert-butoxycarbonyl)piperazin-1-yl]phenylboronic acid

Guidance literature:: 4-(2-bromophenyl)piperazine-1-carboxylic acid tert-butyl ester; With n-butyllithium; In tetrahydrofuran; hexane; at -70 ℃; for 1h;

With isopropyldiisopropoxyborane; In tetrahydrofuran; hexane; at -70 - 20 ℃; for 1.16667h;

With water; ammonium chloride; In tetrahydrofuran; hexane; isopropyl alcohol; for 0.5h;

Reference yield: 37.0%

: 915770-01-3
2-[(4-tert-butoxycarbonyl)piperazin-1-yl]phenylboronic acid

: 86544-77-6
3,3,5,5-tetramethylcyclohex-1-enyl trifluoromethanesulfonate

: 859217-86-0
4-[2-(3,3,5,5-tetramethylcyclohex-1-enyl)phenyl]piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With 2-dicyclohexylphosphino-2',6'-diethoxybiphenyl; cesium fluoride; palladium diacetate; In 1,2-dimethoxyethane; water; at 50 ℃; for 4h; Product distribution / selectivity;