4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide

Base Information

Chemical Name:4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide
CAS No.:889459-00-1
Molecular Formula:C15H19NO7S
Molecular Weight:357.384
Hs Code.:2934100090

Synonyms:889459-00-1;4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide;(4S)-2,2-Dioxido-4-(benzyloxycarbonyl)-1,2,3-oxathiazolidine, N-BOC protected;SCHEMBL1562376;VUNBZHYPHYZUEV-LBPRGKRZSA-N;CS-0104477;D76382;(S)-2,2-dioxo-2lambda6-[1,2,3]oxathiazolidine-3,4-dicarboxylic acid 4-benzyl ester 3-tert-butyl ester

Suppliers and Price of 4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide

Chemical Property:

Melting Point:120 - 122 °C
PSA：107.59000
LogP:2.62920
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:357.08822312
Heavy Atom Count:24
Complexity:570

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C(COS1(=O)=O)C(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(C)(C)OC(=O)N1[C@@H](COS1(=O)=O)C(=O)OCC2=CC=CC=C2

Technology Process of 4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide

There total 4 articles about 4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 59524-02-6
N-tert-butoxycarbonyl-L-serine benzyl ester

: 889459-00-1
4(S)-benzyl-3-tert-butyl-1,2,3-oxathiazolidine-3,4-dicarboxylate-2,2-dioxide

Guidance literature:: N-tert-butoxycarbonyl-L-serine benzyl ester; With 1H-imidazole; thionyl chloride; In dichloromethane; at -78 - 20 ℃;

With ruthenium(IV) oxide; sodium periodate; In water; ethyl acetate; at 0 ℃; for 0.5h;

Reference yield:

: C₁₅H₁₉NO₆S

: 889459-00-1
4(S)-benzyl-3-tert-butyl-1,2,3-oxathiazolidine-3,4-dicarboxylate-2,2-dioxide

Guidance literature:: With sodium periodate; ruthenium(III) trichloride hydrate; In water; acetonitrile; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1039/c4ob01047g

Reference yield:

: C₈H₁₄NO₅^(1-)*K⁽¹⁺⁾

: 889459-00-1
4(S)-benzyl-3-tert-butyl-1,2,3-oxathiazolidine-3,4-dicarboxylate-2,2-dioxide

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 16 h / 20 °C

2: thionyl chloride; pyridine / acetonitrile / 3.5 h / -42 °C / Inert atmosphere

3: sodium periodate; ruthenium(III) trichloride hydrate / water; acetonitrile / 4.25 h / 0 - 20 °C

With pyridine; sodium periodate; thionyl chloride; ruthenium(III) trichloride hydrate; In water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmc.2014.07.023