(S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

Base Information

Chemical Name:(S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid
CAS No.:1620620-10-1
Molecular Formula:C₁₈H₂₇NO₅
Molecular Weight:337.416
Hs Code.:

Synonyms:(S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

Suppliers and Price of (S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

There total 4 articles about (S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 88-18-6
2-tert-Butylphenol

: 1620620-04-3
3(S)-(tert-butoxycarbonyl)-1,2,3-oxathiazolidine-4-carboxylicacid-2,2-dioxide

: 1620620-10-1
(S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

Guidance literature:: 2-tert-Butylphenol; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.166667h; Inert atmosphere;

3(S)-(tert-butoxycarbonyl)-1,2,3-oxathiazolidine-4-carboxylicacid-2,2-dioxide; In tetrahydrofuran; mineral oil; at 0 ℃; for 4h; Inert atmosphere;

With sodium hydrogen sulfate; In tetrahydrofuran; water; mineral oil; pH=2; regioselective reaction; Inert atmosphere;
DOI:10.1039/c4ob01047g

Reference yield:

: 889459-00-1
4(S)-benzyl-3-tert-butyl-1,2,3-oxathiazolidine-3,4-dicarboxylate-2,2-dioxide

: 1620620-10-1
(S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 0.5 h / 20 °C / 760.05 Torr / Inert atmosphere

2.1: sodium hydride / mineral oil; tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

2.2: 4 h / 0 °C / Inert atmosphere

2.3: pH 2 / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; ethyl acetate; mineral oil;
DOI:10.1039/c4ob01047g

Reference yield:

: C₁₅H₁₉NO₆S

: 1620620-10-1
(S)-2-((tert-butoxycarbonyl)amino)-3-(2-tert-butylphenoxy)propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: ruthenium(III) trichloride hydrate; sodium periodate / acetonitrile; water / 1 h / 0 °C / Inert atmosphere

2.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 0.5 h / 20 °C / 760.05 Torr / Inert atmosphere

3.1: sodium hydride / mineral oil; tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

3.2: 4 h / 0 °C / Inert atmosphere

3.3: pH 2 / Inert atmosphere

With sodium periodate; ruthenium(III) trichloride hydrate; palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; water; ethyl acetate; acetonitrile; mineral oil;
DOI:10.1039/c4ob01047g