methyl 4-hydroxy-6,7-dimethoxy-5-(methoxymethoxy)naphthalene-2-carboxylate

Base Information

• Chemical Name: methyl 4-hydroxy-6,7-dimethoxy-5-(methoxymethoxy)naphthalene-2-carboxylate
• CAS No.: 104197-38-8
• Molecular Formula: C₁₆H₁₈O₇
• Molecular Weight: 322.315
• Mol file: 104197-38-8.mol

Synonyms:2-Naphthalenecarboxylic acid, 4-hydroxy-6,7-diMethoxy-5-(MethoxyMethoxy)-, Methyl ester

Chemical Property of methyl 4-hydroxy-6,7-dimethoxy-5-(methoxymethoxy)naphthalene-2-carboxylate

Chemical Property:

• Vapor Pressure: 1.53E-10mmHg at 25°C
• Boiling Point: 498°C at 760 mmHg
• Flash Point: 181.9°C
• PSA: 83.45000
• Density: 1.265g/cm³
• LogP: 2.33190

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 4-hydroxy-6,7-dimethoxy-5-(methoxymethoxy)naphthalene-2-carboxylate

There total 1 articles about methyl 4-hydroxy-6,7-dimethoxy-5-(methoxymethoxy)naphthalene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6,7-Dimethoxy-5-methoxymethoxy-4-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester (104197-37-7) → 4-Hydroxy-6,7-dimethoxy-5-methoxymethoxy-naphthalene-2-carboxylic acid methyl ester (104197-38-8) + 4-Hydroxy-6,7-dimethoxy-5-methoxymethoxy-3-phenylselanyl-naphthalene-2-carboxylic acid methyl ester

Guidance literature:

With Phenylselenyl bromide; lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1021/jo00370a037

Reference yield: 71.0%

4-Hydroxy-6,7-dimethoxy-5-methoxymethoxy-naphthalene-2-carboxylic acid methyl ester (104197-38-8) + dimethyl sulfate (77-78-1) → 4,6,7-Trimethoxy-5-methoxymethoxy-naphthalene-2-carboxylic acid methyl ester (104197-39-9)

Guidance literature:

DOI:10.1021/jo00370a037

upstream raw materials:

6,7-Dimethoxy-5-methoxymethoxy-4-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

Downstream raw materials:

4,6,7-Trimethoxy-5-methoxymethoxy-naphthalene-2-carboxylic acid methyl ester