Acetamide, N-(2-chloro-4-methyl-5-pyrimidinyl)-

Base Information

Chemical Name:Acetamide, N-(2-chloro-4-methyl-5-pyrimidinyl)-
CAS No.:633328-96-8
Molecular Formula:C₇H₈ClN₃O
Molecular Weight:185.613
Hs Code.:2933599090
Mol file:633328-96-8.mol

Synonyms:Acetamide, N-(2-chloro-4-methyl-5-pyrimidinyl)-;N-(2-CHLORO-4-METHYLPYRIMIDIN-5-YL)ACETAMIDE

Suppliers and Price of Acetamide, N-(2-chloro-4-methyl-5-pyrimidinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(2-Chloro-4-methylpyrimidin-5-yl)acetamide
50mg
$ 220.00

Crysdot
N-(2-Chloro-4-methylpyrimidin-5-yl)acetamide 95+%
1g
$ 673.00

Alichem
N-(2-Chloro-4-methylpyrimidin-5-yl)acetamide
1g
$ 682.64

Alichem
N-(2-Chloro-4-methylpyrimidin-5-yl)acetamide
250mg
$ 268.32

Total 2 raw suppliers

Chemical Property of Acetamide, N-(2-chloro-4-methyl-5-pyrimidinyl)-

Chemical Property:

PSA：58.37000
LogP:2.04630

Purity/Quality:

95% ^*data from raw suppliers

N-(2-Chloro-4-methylpyrimidin-5-yl)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Acetamide, N-(2-chloro-4-methyl-5-pyrimidinyl)-

There total 2 articles about Acetamide, N-(2-chloro-4-methyl-5-pyrimidinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 20090-69-1
2-chloro-4-methyl-5-aminopyrimidine

: 108-24-7
acetic anhydride

: 633328-96-8
N-(2-chloro-4-methylpyrimidin-5-yl)acetamide

Guidance literature:: With triethylamine; In dichloromethane; at 25 ℃; for 16h;

Reference yield:

: 20090-69-1
2-chloro-4-methyl-5-aminopyrimidine

: 108-24-7
acetic anhydride

: 64-19-7,77671-22-8
acetic acid

: 633328-96-8
N-(2-chloro-4-methylpyrimidin-5-yl)acetamide

Guidance literature:: at 20 ℃;
DOI:10.1016/j.bmcl.2020.127551

Reference yield:

: 633328-96-8
N-(2-chloro-4-methylpyrimidin-5-yl)acetamide

: 1393181-01-5
5-chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic anhydride; potassium acetate; isopentyl nitrite / chloroform / Reflux

2.1: hydrogenchloride / tetrahydrofuran / 50 °C / Reflux

3.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / C

3.2: 0 - 20 °C

With hydrogenchloride; potassium tert-butylate; potassium acetate; acetic anhydride; isopentyl nitrite; In tetrahydrofuran; chloroform;