5-((6-Chloropyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine

Base Information

• Chemical Name: 5-((6-Chloropyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine
• CAS No.: 1000787-76-7
• Molecular Formula: C17H11ClFN5
• Molecular Weight: 339.759
• Hs Code.: 2933990090
• Mol file: 1000787-76-7.mol

Synonyms:5-((6-Chloropyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine

Chemical Property of 5-((6-Chloropyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine

Chemical Property:

• PSA: 56.49000
• LogP: 3.72910

Purity/Quality:

98%min ^*data from raw suppliers

5-((6-Chloropyridazin-3-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-((6-Chloropyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine

There total 2 articles about 5-((6-Chloropyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-fluorophenyl)-3H-imidazo[4,5-c]pyridine (89075-43-4) + 3-chloro-6-pyridazinyl methyl chloride (120276-59-7) → 5-[6-chloro-pyridazin-3-ylmethyl]-2-(2-fluoro-phenyl)-5H-imidazo[4,5-c]pyridine (1000787-76-7)

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; for 3h;

Reference yield:

3-chloro-6-methylpyridazine (1121-79-5) → 5-[6-chloro-pyridazin-3-ylmethyl]-2-(2-fluoro-phenyl)-5H-imidazo[4,5-c]pyridine (1000787-76-7)

Guidance literature:

Multi-step reaction with 2 steps

1: trichloroisocyanuric acid / chloroform / 1.5 h / 60 °C

2: sodium hydroxide / N,N-dimethyl-formamide / 3 h

With trichloroisocyanuric acid; sodium hydroxide; In chloroform; N,N-dimethyl-formamide;

Reference yield:

2,4-bis(trifluoromethyl)phenylboronic acid (153254-09-2) + 5-[6-chloro-pyridazin-3-ylmethyl]-2-(2-fluoro-phenyl)-5H-imidazo[4,5-c]pyridine (1000787-76-7) → 5-((6-(2,4-bis(trifluoromethyl)phenyl)pyridazin-3-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine (1000787-75-6)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 80 ℃; for 72h; Product distribution / selectivity;

upstream raw materials:

2-(2-fluorophenyl)-3H-imidazo[4,5-c]pyridine

3-chloro-6-pyridazinyl methyl chloride

3-chloro-6-methylpyridazine

Downstream raw materials:

5-((6-(2,4-bis(trifluoromethyl)phenyl)pyridazin-3-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1000787-76-7 5-((6-Chloropyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send