1-Piperidinecarboxylic acid, 4-[2-hydroxy-1-(2-phenyl-1H-benziMidazol-1-yl)ethyl]-, 1,1-diMethylethyl ester

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 4-[2-hydroxy-1-(2-phenyl-1H-benziMidazol-1-yl)ethyl]-, 1,1-diMethylethyl ester
CAS No.:1440753-74-1
Molecular Formula:C25H31N3O3
Molecular Weight:421.539
Hs Code.:
Mol file:1440753-74-1.mol

Synonyms:1-Piperidinecarboxylic acid, 4-[2-hydroxy-1-(2-phenyl-1H-benziMidazol-1-yl)ethyl]-, 1,1-diMethylethyl ester

Suppliers and Price of 1-Piperidinecarboxylic acid, 4-[2-hydroxy-1-(2-phenyl-1H-benziMidazol-1-yl)ethyl]-, 1,1-diMethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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ChemScene
1-Piperidinecarboxylicacid,4-[2-hydroxy-1-(2-phenyl-1H-benzimidazol-1-yl)ethyl]-,1,1-dimethylethylester
1g
$ 2000.00

Total 6 raw suppliers

Chemical Property of 1-Piperidinecarboxylic acid, 4-[2-hydroxy-1-(2-phenyl-1H-benziMidazol-1-yl)ethyl]-, 1,1-diMethylethyl ester

Chemical Property:

PSA：67.59000
LogP:4.82170

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-Piperidinecarboxylicacid,4-[2-hydroxy-1-(2-phenyl-1H-benzimidazol-1-yl)ethyl]-,1,1-dimethylethylester ^*data from reagent suppliers

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Hazard Codes:

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Technology Process of 1-Piperidinecarboxylic acid, 4-[2-hydroxy-1-(2-phenyl-1H-benziMidazol-1-yl)ethyl]-, 1,1-diMethylethyl ester

There total 8 articles about 1-Piperidinecarboxylic acid, 4-[2-hydroxy-1-(2-phenyl-1H-benziMidazol-1-yl)ethyl]-, 1,1-diMethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1440753-63-8
tert-butyl 4-(2-(benzyl(tert-butoxycarbonyl)amino)-2-oxo-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate

: 1440753-74-1
tert-butyl 4-(2-hydroxy-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate

Guidance literature:: With sodium tetrahydroborate; ethanol; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

: 1440753-53-6
N-benzyl-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)-2-(piperidin-4-yl)acetamide

: 1440753-74-1
tert-butyl 4-(2-hydroxy-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; dmap / dichloromethane / 17 h / 20 °C

2: sodium tetrahydroborate; ethanol / tetrahydrofuran / 16 h / 20 °C

With dmap; sodium tetrahydroborate; ethanol; triethylamine; In tetrahydrofuran; dichloromethane;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1440753-74-1
tert-butyl 4-(2-hydroxy-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; dmap / dichloromethane / 17 h / 20 °C

2: sodium tetrahydroborate; ethanol / tetrahydrofuran / 16 h / 20 °C

With dmap; sodium tetrahydroborate; ethanol; triethylamine; In tetrahydrofuran; dichloromethane;