2-(Methylsulfonyl)pyrimidine-5-carboxylic acid

Base Information

Chemical Name:2-(Methylsulfonyl)pyrimidine-5-carboxylic acid
CAS No.:914208-17-6
Molecular Formula:C6H6N2O4S
Molecular Weight:202.191
Hs Code.:2933599090
European Community (EC) Number:893-147-2
DSSTox Substance ID:DTXSID90593996
Wikidata:Q82488676
Mol file:914208-17-6.mol

Synonyms:914208-17-6;2-(Methylsulfonyl)pyrimidine-5-carboxylic acid;2-methanesulfonylpyrimidine-5-carboxylic acid;2-methylsulfonylpyrimidine-5-carboxylic acid;2-methanesulfonyl-pyrimidine-5-carboxylic acid;MFCD08690748;SCHEMBL335350;DTXSID90593996;LNADHOIWAYQWPG-UHFFFAOYSA-N;AKOS022176378;SY355065;DB-330408;CS-0210457;2-(Methylsulfonyl)pyrimidine-5-carboxylicacid;2-(Methanesulfonyl)pyrimidine-5-carboxylic acid;G55801;EN300-8165652;F2147-8629;Z1269170584;2-(Methylsulfonyl)pyrimidine-5-carboxylic Acid2-(Methylsulfonyl)pyrimidine-5-carboxylic Acid

Suppliers and Price of 2-(Methylsulfonyl)pyrimidine-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(Methylsulfonyl)pyrimidine-5-carboxylicacid 95+%
1g
$ 313.00

Chemenu
2-(methylsulfonyl)pyrimidine-5-carboxylicacid 95%
1g
$ 296.00

Total 5 raw suppliers

Chemical Property of 2-(Methylsulfonyl)pyrimidine-5-carboxylic acid

Chemical Property:

PSA：105.60000
LogP:0.65910
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:202.00482785
Heavy Atom Count:13
Complexity:286

Purity/Quality:

99%, ^*data from raw suppliers

2-(Methylsulfonyl)pyrimidine-5-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)(=O)C1=NC=C(C=N1)C(=O)O
Uses 2-Methylsulfonylpyrimidine-5-carboxylic Acid can be used to synthesize antibody drug conjugates.

Technology Process of 2-(Methylsulfonyl)pyrimidine-5-carboxylic acid

There total 1 articles about 2-(Methylsulfonyl)pyrimidine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 110099-94-0
2-(methylsulfanyl)-5-pyrimidinecarboxylic acid

: 914208-17-6
2-(methylsulfonyl)pyrimidine-5-carboxylic acid

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 24h;

Reference yield: 59.0%

: 914208-17-6
2-(methylsulfonyl)pyrimidine-5-carboxylic acid

: N-(6-aminohexanoyl)-L-valyl-N-{4-[(8S,11S,12R)-11-[(2S)-butan-2-yl]-12-(2-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-2-oxoethyl)-5,5,10-trimethyl-3,6,9-trioxo-8-(propan-2-yl)-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N⁵-carbamoyl-L-ornithinamide trifluoroacetate

: N-[6-({[2-(methylsulfonyl)pyrimidin-5-yl]carbonyl}amino)hexanoyl]-L-valyl-N-{4-[(8S,11S,12R)-11-[(2S)-butan-2-yl]-12-(2-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-2-oxoethyl)-5,5,10-trimethyl-3,6,9-trioxo-8-(propan-2-yl)-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N⁵-carbamoyl-L-omithinamide

Guidance literature:: With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; In tetrahydrofuran; at 20 ℃; for 48h; Inert atmosphere;