2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI)

Base Information

Chemical Name:2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI)
CAS No.:126261-33-4
Molecular Formula:C₁₀H₁₃NO₃
Molecular Weight:195.218
Hs Code.:
Mol file:126261-33-4.mol

Synonyms:2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI)

Suppliers and Price of 2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI)

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI)

There total 6 articles about 2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7677-24-9
trimethylsilyl cyanide

: 148217-21-4
Acetic acid (3aS,5S,6aS)-2-ethoxy-hexahydro-cyclopenta[b]furan-5-yl ester

: 148217-22-5,126261-33-4
Acetic acid (2S,3aS,5S,6aS)-2-cyano-hexahydro-cyclopenta[b]furan-5-yl ester

: 148217-23-6,126261-33-4
Acetic acid (2R,3aS,5S,6aS)-2-cyano-hexahydro-cyclopenta[b]furan-5-yl ester

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -40 ℃; for 2h; Yield given. Yields of byproduct given;
DOI:10.1021/jm00061a012

Reference yield:

: 7677-24-9
trimethylsilyl cyanide

: 148217-21-4
Acetic acid (3aS,5S,6aS)-2-ethoxy-hexahydro-cyclopenta[b]furan-5-yl ester

: 148217-22-5,126261-33-4
Acetic acid (2S,3aS,5S,6aS)-2-cyano-hexahydro-cyclopenta[b]furan-5-yl ester

: 148217-23-6,126261-33-4
Acetic acid (2R,3aS,5S,6aS)-2-cyano-hexahydro-cyclopenta[b]furan-5-yl ester

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -40 ℃; for 2h; Yield given. Yields of byproduct given;
DOI:10.1021/jm00061a012

Reference yield:

: 60410-16-4
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

: 148217-23-6,126261-33-4
Acetic acid (2R,3aS,5S,6aS)-2-cyano-hexahydro-cyclopenta[b]furan-5-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / N-iodosuccinimide / CH₂Cl₂ / 4 h / -20 °C

2: 77 percent / N-Bu₃SnH, AIBN / benzene / 0.5 h / Heating

3: (trimethylsilyl)trifluoromethane sulfonate / CH₂Cl₂ / 2 h / -40 °C

With N-iodo-succinimide; 2,2'-azobis(isobutyronitrile); trimethylsilyl trifluoromethanesulfonate; tri-n-butyl-tin hydride; In dichloromethane; benzene;
DOI:10.1021/jm00061a012