6-(tert-ButoxycarbonylaMino)-1H-indole-2-carboxylic acid

Base Information

Chemical Name:6-(tert-ButoxycarbonylaMino)-1H-indole-2-carboxylic acid
CAS No.:1093261-27-8
Molecular Formula:C14H16N2O4
Molecular Weight:276.292
Hs Code.:
Mol file:1093261-27-8.mol

Synonyms:6-(tert-ButoxycarbonylaMino)-1H-indole-2-carboxylic acid;6-[[(1,1-dimethylethoxy)carbonyl]amino]-1H-Indole-2-carboxylic acid

Suppliers and Price of 6-(tert-ButoxycarbonylaMino)-1H-indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-(tert-ButoxycarbonylaMino)-1H-indole-2-carboxylic acid

Chemical Property:

PSA：94.91000
LogP:3.22670

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-(tert-ButoxycarbonylaMino)-1H-indole-2-carboxylic acid

There total 7 articles about 6-(tert-ButoxycarbonylaMino)-1H-indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 541522-65-0
methyl 6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-1H-indole-2-carboxylate

: 1093261-27-8
6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-1H-indole-2-carboxylic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃;

Reference yield:

: 136818-66-1
6-Nitro-1H-indole-2-carboxylic acid methyl ester

: 1093261-27-8
6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1: dmap / dichloromethane / 1 h / 20 °C

2: hydrogen / platinum(IV) oxide / ethanol / 1 h / 20 °C / 2585.81 Torr / Inert atmosphere

3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

4: triethylamine / dichloromethane / 1 h / 20 °C

5: water; lithium hydroxide / tetrahydrofuran; methanol / 20 °C

With dmap; water; hydrogen; triethylamine; trifluoroacetic acid; lithium hydroxide; platinum(IV) oxide; In tetrahydrofuran; methanol; ethanol; dichloromethane;

Reference yield:

: 10242-00-9
6-Nitro-1H-indole-2-carboxylic Acid

: 1093261-27-8
6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1: sulfuric acid / 2 h / Reflux

2: dmap / dichloromethane / 1 h / 20 °C

3: hydrogen / platinum(IV) oxide / ethanol / 1 h / 20 °C / 2585.81 Torr / Inert atmosphere

4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

5: triethylamine / dichloromethane / 1 h / 20 °C

6: water; lithium hydroxide / tetrahydrofuran; methanol / 20 °C

With dmap; sulfuric acid; water; hydrogen; triethylamine; trifluoroacetic acid; lithium hydroxide; platinum(IV) oxide; In tetrahydrofuran; methanol; ethanol; dichloromethane;