6-Chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside

Base Information

Chemical Name:6-Chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside
CAS No.:135473-21-1
Molecular Formula:C10H10ClFN4O3
Molecular Weight:288.666
Hs Code.:
Mol file:135473-21-1.mol

Synonyms:6-Chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside;6-Chloro-9-(2-deoxy-2-fluoro--D-arabinofuranosyl)purine;6-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purine

Suppliers and Price of 6-Chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2R,3R,4S,5R)-5-(6-Chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol 97%
5mg
$ 980.00

Crysdot
(2R,3R,4S,5R)-5-(6-Chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol 97%
10mg
$ 1450.00

Chemenu
(2R,3R,4S,5R)-5-(6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol 97%
10mg
$ 1356.00

Alichem
(2R,3R,4S,5R)-5-(6-Chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
10mg
$ 1566.00

Alichem
(2R,3R,4S,5R)-5-(6-Chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
5mg
$ 980.00

Total 6 raw suppliers

Chemical Property of 6-Chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside

Chemical Property:

Melting Point:178 - 180 °C (ethanol)
PSA：93.29000
LogP:0.06840

Purity/Quality:

97% ^*data from raw suppliers

(2R,3R,4S,5R)-5-(6-Chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-Chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside

There total 3 articles about 6-Chloropurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 144927-25-3
6-chloro-9-(2-deoxy-2-fluoro-3,5-di-O-trityl-β-D-arabinofuranosyl)purine

: 135473-21-1
6-chloro-9-(2-deoxy-2-fluoro-O-D-arabinofuranosyl)purine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; Ambient temperature;
DOI:10.1248/cpb.44.2331

Reference yield:

: 2004-06-0
6-Chloropurine riboside

: 135473-21-1
6-chloro-9-(2-deoxy-2-fluoro-O-D-arabinofuranosyl)purine

Guidance literature:: Multi-step reaction with 3 steps

1: 23 percent / DMAP / CH₂Cl₂

2: 87 percent / (diethylamino)sulfur trifluoride; pyridine

3: 60 percent / HCl / dioxane; CH₂Cl₂

With pyridine; hydrogenchloride; dmap; diethylamino-sulfur trifluoride; In 1,4-dioxane; dichloromethane;
DOI:10.1081/NCN-120021951

Reference yield:

: 144925-68-8
9-(3',5'-di-O-trityl-β-D-ribofuranosyl)-6-chloropurine

: 135473-21-1
6-chloro-9-(2-deoxy-2-fluoro-O-D-arabinofuranosyl)purine

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / (diethylamino)sulfur trifluoride; pyridine

2: 60 percent / HCl / dioxane; CH₂Cl₂

With pyridine; hydrogenchloride; diethylamino-sulfur trifluoride; In 1,4-dioxane; dichloromethane;
DOI:10.1081/NCN-120021951