Benzaldehyde, 4-(1H-imidazol-1-yl)-3-methoxy-

Base Information

• Chemical Name: Benzaldehyde, 4-(1H-imidazol-1-yl)-3-methoxy-
• CAS No.: 870837-70-0
• Molecular Formula: C11H10N2O2
• Molecular Weight: 202.213
• Mol file: 870837-70-0.mol

Synonyms:Benzaldehyde, 4-(1H-imidazol-1-yl)-3-methoxy-;4-(1H-iMidazol-1-yl)-3-Methoxybenzaldehyde

Chemical Property of Benzaldehyde, 4-(1H-imidazol-1-yl)-3-methoxy-

Chemical Property:

• Vapor Pressure: 1.03E-06mmHg at 25°C
• Boiling Point: 403.2°C at 760 mmHg
• Flash Point: 197.7°C
• PSA: 44.12000
• Density: 1.18g/cm³
• LogP: 1.69340
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-Imidazol-1-yl-3-methoxy-benzaldehyde 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzaldehyde, 4-(1H-imidazol-1-yl)-3-methoxy-

There total 12 articles about Benzaldehyde, 4-(1H-imidazol-1-yl)-3-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

C11H12N2O2 (1269834-33-4) → 4-(1H-imidazol-1-yl)-3-methoxybenzaldehyde (870837-70-0)

Guidance literature:

With oxalyl dichloride; In dichloromethane; dimethyl sulfoxide; at -60 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.bmcl.2010.12.020

Reference yield:

1H-imidazole (288-32-4) + 4-fluoro-3-methoxybenzaldehyde (128495-46-5) → 4-(1H-imidazol-1-yl)-3-methoxybenzaldehyde (870837-70-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield:

1H-imidazole (288-32-4) + 3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde (870837-18-6) → 4-(1H-imidazol-1-yl)-3-methoxybenzaldehyde (870837-70-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 130 ℃;

upstream raw materials:

1H-imidazole

3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde

4-fluoro-3-methoxybenzaldehyde

C₁₁H₁₂N₂O₂

Downstream raw materials:

4-(5-chloro-1H-imidazol-1-yl)-3-methoxybenzaldehyde

4-(2-chloro-1H-imidazol-1-yl)-3-methoxybenzaldehyde

4-(1H-imidazol-1-yl)-3-methoxybenzoic acid

1-(4-ethynyl-2-methoxyphenyl)-1H-imidazole