2-(1-Naphthalenylcarbonyl)-propanedinitrile

Base Information

Chemical Name:2-(1-Naphthalenylcarbonyl)-propanedinitrile
CAS No.:1236038-48-4
Molecular Formula:C₁₄H₈N₂O
Molecular Weight:220.23
Hs Code.:
Mol file:1236038-48-4.mol

Synonyms:2-(1-Naphthalenylcarbonyl)-propanedinitrile

Suppliers and Price of 2-(1-Naphthalenylcarbonyl)-propanedinitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(1-Naphthalenylcarbonyl)propanedinitrile
50mg
$ 305.00

Matrix Scientific
2-(1-Naphthoyl)malononitrile 97%
25g
$ 3240.00

Matrix Scientific
2-(1-Naphthoyl)malononitrile 97%
5g
$ 1080.00

Crysdot
2-(1-Naphthoyl)malononitrile 95+%
5g
$ 1072.00

Chemenu
2-(1-Naphthoyl)malononitrile 95%
5g
$ 1010.00

American Custom Chemicals Corporation
2-(1-NAPHTHALENYLCARBONYL)PROPANEDINITRILE 95.00%
250MG
$ 255.15

Total 7 raw suppliers

Chemical Property of 2-(1-Naphthalenylcarbonyl)-propanedinitrile

Chemical Property:

PSA：64.65000
LogP:2.68586
Solubility.:Chloroform, Ethyl Acetate

Purity/Quality:

≥95% ^*data from raw suppliers

2-(1-Naphthalenylcarbonyl)propanedinitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-(1-Naphthalenylcarbonyl)-propanedinitrile is used in the preparation of inhibitors that target calcium-dependent protein kinases in C. parvum and T. gondii parazites.

Technology Process of 2-(1-Naphthalenylcarbonyl)-propanedinitrile

There total 2 articles about 2-(1-Naphthalenylcarbonyl)-propanedinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 109-77-3
malononitrile

: 879-18-5
naphthalene-1-carbonic acid chloride

: 1236038-48-4
C₁₄H₈N₂O

Guidance literature:: With sodium hydride; In tetrahydrofuran; paraffin oil (nujol); at 5 - 10 ℃; for 3h;

Reference yield:

: 86-55-5
1-naphthalenecarboxylic acid

: 1236038-48-4
C₁₄H₈N₂O

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / N,N-dimethyl-formamide; hexane / 1 h / 20 °C

2: sodium hydride / tetrahydrofuran / 1 h / 20 °C

With oxalyl dichloride; sodium hydride; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1021/jm4001314

Reference yield:

: 1236038-48-4
C₁₄H₈N₂O

: 221243-34-1
5-amino-1-tert-butyl-3-naphthalen-1-yl-1H-pyrazole-4-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / water; 1,4-dioxane / 1 h / Reflux

2: ethanol / 1 h / Reflux

With sodium hydrogencarbonate; In 1,4-dioxane; ethanol; water;
DOI:10.1021/jm4001314