5,6-Dibromo-2-chloro-1H-1,3-benzodiazole

Base Information

• Chemical Name: 5,6-Dibromo-2-chloro-1H-1,3-benzodiazole
• CAS No.: 142356-67-0
• Molecular Formula: C7H3Br2ClN2
• Molecular Weight: 310.375
• Hs Code.: 2933990090
• Mol file: 142356-67-0.mol

Synonyms:5,6-Dibromo-2-chloro-1H-1,3-benzodiazole

Chemical Property of 5,6-Dibromo-2-chloro-1H-1,3-benzodiazole

Chemical Property:

• PSA: 28.68000
• LogP: 3.74130

Purity/Quality:

97% ^*data from raw suppliers

5,6-Dibromo-2-chloro-1H-1,3-benzodiazole >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,6-Dibromo-2-chloro-1H-1,3-benzodiazole

There total 1 articles about 5,6-Dibromo-2-chloro-1H-1,3-benzodiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2-chloro-1H-benzoimidazole (4857-06-1) → 5,6-dibromo-2-chloro-1H-benzimidazole (142356-67-0)

Guidance literature:

With bromine; acetic acid; at 50 ℃; for 1.5h;

Reference yield: 58.0%

p-toluenesulfonyl chloride (98-59-9) + 5,6-dibromo-2-chloro-1H-benzimidazole (142356-67-0) → 5,6-dibromo-2-chloro-1-tosyl-1H-benzimidazole

Guidance literature:

5,6-dibromo-2-chloro-1H-benzimidazole; With dmap; In acetonitrile; at 20 ℃; for 0.5h;

p-toluenesulfonyl chloride; In acetonitrile; at 40 - 50 ℃;

DOI:10.1016/j.bmc.2018.05.015

Reference yield: 55.0%

4-Nitrobenzenesulfonyl chloride (98-74-8) + 5,6-dibromo-2-chloro-1H-benzimidazole (142356-67-0) → 5,6-dibromo-2-chloro-1-(4-nitrophenylsulfonyl)-1H-benzimidazole

Guidance literature:

5,6-dibromo-2-chloro-1H-benzimidazole; With dmap; In acetonitrile; at 20 ℃; for 0.5h;

4-Nitrobenzenesulfonyl chloride; In acetonitrile; at 40 - 50 ℃;

DOI:10.1016/j.bmc.2018.05.015

upstream raw materials:

2-chloro-1H-benzoimidazole