Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1S,2R)- (9CI)

Base Information

• Chemical Name: Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1S,2R)- (9CI)
• CAS No.: 156292-48-7
• Molecular Formula: C₇H₁₁NO₂
• Molecular Weight: 141.17
• Mol file: 156292-48-7.mol

Synonyms:Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1S,2R)- (9CI)

Chemical Property of Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1S,2R)- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1S,2R)- (9CI)

There total 16 articles about Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1S,2R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(2E)-3-phenyl-2-propenyl (1R,2S)-4-methylene-2-{[(2E)-3-phenyl-2-propenyloxycarbonyl]amino}cyclopentanecarboxylate (198022-62-7) → (-)-(1R,2S)-2-amino-4-methylenecyclopentanecarboxylic acid (198022-65-0,156292-16-9,156292-48-7,755750-29-9,526194-96-7,786615-32-5)

Guidance literature:

With morpholine; palladium diacetate; triphenylphosphine; In ethanol;

DOI:10.1016/S0960-894X(02)00958-7

Reference yield:

→ isoleucine (319-78-8,443-79-8,1509-34-8,1509-35-9,3107-04-8,7004-09-3,73-32-5,959215-79-3,18875-42-8) + (-)-(1R,2S)-2-amino-4-methylenecyclopentanecarboxylic acid (198022-65-0,156292-16-9,156292-48-7,755750-29-9,526194-96-7,786615-32-5)

Guidance literature:

Reference yield:

(E)-Cinnamyl (1S,2R)-2-N-((E)-cinnamyloxycarbonyl)amino-4-methylene-1-cyclopentane-carboxylate (198022-63-8) → (+)-(1S,2R)-2-Amino-4-methylene-cyclopentane-1-carboxylic acid (156292-16-9,156292-48-7,755750-29-9,526194-96-7,786615-32-5)

Guidance literature:

With morpholine; palladium diacetate; triphenylphosphine; In ethanol;

DOI:10.1016/S0960-894X(02)00958-7

upstream raw materials:

(2E)-3-phenyl-2-propenyl (1R,2S)-4-methylene-2-{[(2E)-3-phenyl-2-propenyloxycarbonyl]amino}cyclopentanecarboxylate

1,2,3,4-butanetetracarboxylic acid

1,2,3,4-butanetetracarboxylic acid tetraethyl ester

4-Methylene-cyclopentane-1,2-dicarboxylic acid diethyl ester

Downstream raw materials:

(-)-(1R,5S)-5-amino-3-methyl-cyclopent-2-enecarboxylic acid

(+)-(1R,2S)-2-amino-4-methyl-cyclopent-3-enecarboxylic acid