PE 154

Base Information

• Chemical Name: PE 154
• CAS No.: 1192750-33-6
• Molecular Formula: C35H35N5O4
• Molecular Weight: 589.68
• Mol file: 1192750-33-6.mol

Synonyms:PE 154;2-(1,2,3,4-Tetrahydro-9-acridinyl)hydrazide-4-[[[7-(diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid

Chemical Property of PE 154

Chemical Property:

• PSA: 112.66000
• LogP: 6.28020
• Storage Temp.: 2-8°C
• Solubility.: DMSO: soluble10mg/mL, clear (warmed)

Purity/Quality:

98%Min ^*data from raw suppliers

PE 154 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: PE 154 is a potent and fluorescent inhibitor of human acetylcholinesterase

Technology Process of PE 154

There total 1 articles about PE 154 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

2-(4-aminophenyl)-N'-1,2,3,4-tetrahydroacridin-9-ylacetohydrazide (1192750-32-5) + 7-(diethylamino)-4-hydroxy-2H-chromen-2-one (64369-55-7) + orthoformic acid triethyl ester (122-51-0) → 2-(4-(((7-(diethylamino)-2,4-dioxo-2H-chromen-3(4H)-ylidene)methyl)amino)phenyl)-N'-1,2,3,4-tetrahydroacridin-9-ylacetohydrazide (1192750-33-6)

Guidance literature:

In acetic acid; for 2.16h; Reflux;

DOI:10.1039/b909612d

upstream raw materials:

2-(4-aminophenyl)-N'-1,2,3,4-tetrahydroacridin-9-ylacetohydrazide

7-(diethylamino)-4-hydroxy-2H-chromen-2-one

orthoformic acid triethyl ester