64369-55-7

Basic information

• Product Name: 4-HYDROXY-7-DIETHIAMINO-COUMARINE
• Synonyms: 4-HYDROXY-7-DIETHIAMINO-COUMARINE ;2H-1-Benzopyran-2-one, 7-(diethylamino)-4-hydroxy-
• CAS NO: 64369-55-7
• Molecular Formula: C₁₃H₁₅NO₃
• Molecular Weight: 241.28678
• Mol File: 64369-55-7.mol
• Article Data: 31

Chemical Properties

• Melting Point: 236 °C(Solv: isopropanol (67-63-0))
• Boiling Point: 432.685°C at 760 mmHg
• Flash Point: 215.48°C
• Appearance: /
• Density: 1.274g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.627
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: 4-HYDROXY-7-DIETHIAMINO-COUMARINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-7-DIETHIAMINO-COUMARINE(64369-55-7)
• EPA Substance Registry System: 4-HYDROXY-7-DIETHIAMINO-COUMARINE(64369-55-7)

Safety Data

• Hazardous Substances Data: 64369-55-7(Hazardous Substances Data)

Usage

Uses

Has applications involving cholinesterase inhibitors for β-amyloid plaques as well as synthesis of fluorescent dyes based on coumarin.

InChI:InChI=1/C13H15NO3/c1-3-14(4-2)9-5-6-10-11(15)8-13(16)17-12(10)7-9/h5-8,15H,3-4H2,1-2H3

Upstream product

• 91-68-9 3-diethylaminophenol 
• 141-82-2 malonic acid 
• 108-95-2 phenol 
• 1969-44-4 diphenyl malonate 
• 15781-70-1 malonic acid bis-(2,4,6-trichloro-phenyl) ester 
• 52994-51-1 bis-2,4-dichlorophenyl malonate 

Downstream Products

• 54711-39-6 7-(diethylamino)-2-oxo-2H-1-benzopyran-4-carboxaldehyde 
• 1629670-71-8 C₃₂H₃₁N₂O₉S₂⁽¹⁺⁾*C₂F₃O₂^(1-) 

Relevant articles and documents

Synthesis of novel push-pull fluorescent dyes-7-(diethylamino)furo[3,2-c]coumarin and 7-(diethylamino)thieno[3,2-c]coumarin derivatives

Novel push-pull fluorescent dyes, 7-(diethylamino)furo[3,2-c]coumarin and 7-(diethylamino)thieno[3,2-c]coumarin derivatives, were designed and synthesized using formyl derivatives of furo-and thieno[3,2-c]coumarins as key intermediates. Electron absorption and emission spectra of the dyes were recorded in different solvents. The longest-wave bands in the electron absorption spectra of the dyes are suggested to be of push-pull nature.

BF2 group chelated AIE fluorescent probe for polarity mapping of lipid droplets in cells and in vivo

Lipid droplets (LDs), are multi-functional organelles with the storage of neutral lipids and proteins, participating in various of physiological processes. However, abnormal of LDs in morphology and numbers always lead to multiple diseases, including canc

Coumarin derivative CTT as well as synthesis method and application thereof

The invention provides a coumarin derivative CTT as well as a synthesis method and an application thereof. The derivative CTT is named as ethyl (E)-2-cyano-3-(7-(diethylamino)-2-oxo-4-(p-tolylthio)-2H-chromene-3-yl) ethyl acrylate, and also namely 2-hydro

Copper(II)-Catalyzed Tandem Reaction: Synthesis of Furo[3,2- c]coumarin Derivatives and Evaluation for Photophysical Properties

An efficient protocol for synthesizing furo[3,2-c]coumarin derivatives is described. The novel reaction could afford the desired furocoumarins with good to excellent yields in a mild and rapid manner. Large substrate scope screening and scale-up preparation have also been accomplished, and selected compounds were evaluated for their photophysical properties.