5-Ethoxy-2-phenyl-1,3-oxazole-4-carboxamide

Base Information

Chemical Name:5-Ethoxy-2-phenyl-1,3-oxazole-4-carboxamide
CAS No.:128242-87-5
Molecular Formula:C12H12N2O3
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID00562214
Wikidata:Q82446275
Mol file:128242-87-5.mol

Synonyms:128242-87-5;5-Ethoxy-2-phenyl-1,3-oxazole-4-carboxamide;5-ETHOXY-2-PHENYLOXAZOLE-4-CARBOXAMIDE;DTXSID00562214;AB54844

Suppliers and Price of 5-Ethoxy-2-phenyl-1,3-oxazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-ETHOXY-2-PHENYLOXAZOLE-4-CARBOXAMIDE 95.00%
5MG
$ 498.22

Total 3 raw suppliers

Chemical Property of 5-Ethoxy-2-phenyl-1,3-oxazole-4-carboxamide

Chemical Property:

PSA：78.35000
LogP:2.53950
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:232.08479225
Heavy Atom Count:17
Complexity:267

Purity/Quality:

98%min ^*data from raw suppliers

5-ETHOXY-2-PHENYLOXAZOLE-4-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=C(N=C(O1)C2=CC=CC=C2)C(=O)N

Technology Process of 5-Ethoxy-2-phenyl-1,3-oxazole-4-carboxamide

There total 1 articles about 5-Ethoxy-2-phenyl-1,3-oxazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 54644-14-3
2-phenyl-5-ethoxyoxazole-4-carboxylic acid chloride

: 128242-87-5
2-phenyl-4-(aminocarbonyl)-5-ethoxyoxazole

Guidance literature:: With ammonium hydroxide; for 0.5h; Ambient temperature;
DOI:10.1021/jo00301a056

Reference yield: 66.0%

: 128242-87-5
2-phenyl-4-(aminocarbonyl)-5-ethoxyoxazole

: 128242-93-3
2-phenyl-4-(aminothiocarbonyl)-5-ethoxyoxazole

Guidance literature:: With Lawessons reagent; In tetrahydrofuran; for 2h; Heating;
DOI:10.1021/jo00301a056

Reference yield:

: 128242-87-5
2-phenyl-4-(aminocarbonyl)-5-ethoxyoxazole

: 31785-06-5
5-amino-2-phenylthiazole-4-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / 2,4-bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lawesson's reagent) / tetrahydrofuran / 2 h / Heating

2: 87 percent / toluene / 17 h / Heating

With Lawessons reagent; In tetrahydrofuran; toluene;
DOI:10.1021/jo00301a056