DL-Cyclobutylalanine

Base Information

• Chemical Name: DL-Cyclobutylalanine
• CAS No.: 4426-06-6
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.186
• Hs Code.: 2922499990
• Mol file: 4426-06-6.mol

Synonyms:DL-Cyclobutylalanine;2-aMino-3-cyclobutylpropanoic acid;3-Cyclobutylalanine;Cyclobutanealanine

Chemical Property of DL-Cyclobutylalanine

Chemical Property:

• PSA: 63.32000
• LogP: 1.28880
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-3-cyclobutylpropanoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DL-Cyclobutylalanine

There total 2 articles about DL-Cyclobutylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclobutylmethyl 4-methylbenzenesulfonate (13295-53-9) + 2-acetylaminomalonic acid diethyl ester (1068-90-2) → DL-2-amino-3-cyclobutylpropanoic acid (4426-06-6,1201593-65-8,174266-00-3)

Guidance literature:

Multistep reaction; (i) NaH, DMF, (ii) /BRN= 2377603/, (iii) aq. HCl;

DOI:10.1021/jm00339a001

Reference yield:

(Bromomethyl)cyclobutane (17247-58-4) + 2-acetylaminomalonic acid diethyl ester (1068-90-2) → DL-2-amino-3-cyclobutylpropanoic acid (4426-06-6,1201593-65-8,174266-00-3)

Guidance literature:

Multistep reaction; (i) NaH, DMF, (ii) /BRN= 1071216/, tBuOH, (iii) aq. HCl;

upstream raw materials:

(Bromomethyl)cyclobutane

2-acetylaminomalonic acid diethyl ester

cyclobutylmethyl 4-methylbenzenesulfonate