Cyclobutylmethyl 4-methylbenzenesulfonate

Base Information

• Chemical Name: Cyclobutylmethyl 4-methylbenzenesulfonate
• CAS No.: 13295-53-9
• Molecular Formula: C12H16O3S
• Molecular Weight: 240.323
• Mol file: 13295-53-9.mol

Synonyms:cyclobutanemethanol tosylate;cyclobutylmethyl p-toluenesulphonate;Cyclobutanemethanol,4-methylbenzenesulfonate;p-Toluolsulfonsaeure-cyclobutylmethylester;toluene-p-sulphonate of cyclobutylmethanol;cyclobutylmethyl 4-methylbenzenesulfonate;cyclobutylmethanol O-toluene-4-sulfonate;

Chemical Property of Cyclobutylmethyl 4-methylbenzenesulfonate

Chemical Property:

• PSA: 82.98000
• LogP: 3.10130

Purity/Quality:

98%min ^*data from raw suppliers

Cyclobutylmethyl4-Methylbenzenesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclobutylmethyl 4-methylbenzenesulfonate

There total 7 articles about Cyclobutylmethyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

cyclobutanemethanol (4415-82-1) + p-toluenesulfonyl chloride (98-59-9) → cyclobutylmethyl 4-methylbenzenesulfonate (13295-53-9)

Guidance literature:

With dmap; In dichloromethane; at 0 - 25 ℃;

Reference yield:

cyclobutanemethanol (4415-82-1) + p-toluenesulfonyl chloride (98-59-9) → 6-[N-(5-Chloro-2-cyclobutylmethoxybenzyl)-N-ethylamino]-3-cyanopyridazine + cyclobutylmethyl 4-methylbenzenesulfonate (13295-53-9)

Guidance literature:

With triethylamine; In dichloromethane;

Reference yield:

Cyclobutanecarboxylic acid (3721-95-7) → cyclobutylmethyl 4-methylbenzenesulfonate (13295-53-9)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride

2: lithium aluminum hydride / diethyl ether / 2 h / Heating

3: pyridine

With pyridine; lithium aluminium tetrahydride; thionyl chloride; In diethyl ether;

upstream raw materials:

cyclobutanemethanol

p-toluenesulfonyl chloride

Cyclobutanecarboxylic acid

diethyl cyclobutane-1,1-dicarboxylate

Downstream raw materials:

cyclobutyl acetonitrile

4-(2-cyclobutylmethylthio-ethyl)-1-methoxy-benzene

1-Benzyloxy-4-(3-cyclobutylmethoxy-propyl)-benzene

4-<(cyclobutylmethoxy)ethyl>-1-(phenylmethoxy)benzene