Voriconazole Vfend

Base Information

Chemical Name:Voriconazole Vfend
CAS No.:173967-54-9
Molecular Formula:
Molecular Weight:0
Hs Code.:
Mol file:173967-54-9.mol

Synonyms:Voriconazole Vfend;Vfend;(R-(R*,S*))-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol;4-Pyrimidineethanol, alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-, (R-(R*,S*))-;Drg-0301;Unii-jfu09I87tr;Vrc;(αR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-(Methyl-d3)-α-(1H-1,2,4-triazol-1-ylMethyl)-4-pyriMidineethanol

Suppliers and Price of Voriconazole Vfend

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 38 raw suppliers

Chemical Property of Voriconazole Vfend

Chemical Property:

Storage Temp.:-20°C

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Voriconazole Vfend

There total 156 articles about Voriconazole Vfend which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

: (2R,3S/2S,3R)-6-[4-(3,5-dibromo-1H-1,2,4-triazol-1-yl)-3-(2,4-difluorophenyl)-3-hydroxybutan-2-yl]-5-fluoropyrimidin-4-yl methanesulfonate

: 182230-43-9,137234-63-0,173967-54-9,188416-29-7
2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Guidance literature:: With ammonium formate; palladium on carbon; In toluene; at 80 ℃; for 3h;

Reference yield: 92.0%

: 137234-63-0,173967-54-9,188416-29-7
2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butane-2-ol

: 137234-62-9,137234-63-0,173967-54-9,188416-29-7
voriconazole

Guidance literature:: 2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butane-2-ol; With (1S)-10-camphorsulfonic acid; In methanol; acetone; for 1h; Reflux;

With sodium hydroxide; In dichloromethane; water; pH=11 - 12;