4-Chloro-6-ethyl-5-fluoropyrimidine

Base Information

Chemical Name:4-Chloro-6-ethyl-5-fluoropyrimidine
CAS No.:137234-74-3
Molecular Formula:C6H6ClFN2
Molecular Weight:160.578
Hs Code.:2933599090
European Community (EC) Number:604-010-1
DSSTox Substance ID:DTXSID30587753
Wikidata:Q72450101
Mol file:137234-74-3.mol

Synonyms:4-Chloro-6-ethyl-5-fluoropyrimidine;137234-74-3;PYRIMIDINE, 4-CHLORO-6-ETHYL-5-FLUORO-;MFCD07782087;4-Chloro-6-ethyl-5-fluoro-pyrimidine;EC 604-010-1;SCHEMBL372414;DTXSID30587753;BCP04247;CS-B1291;4-chloro-6-ethyl-5-fluoro pyrimidine;AKOS005063655;AC-4747;PB10473;AS-15052;SY011522;DB-042382;NS00004637;EN300-102307;4-Chloro-6-ethyl-5-fluoropyrimidine, AldrichCPR;Q-102789;F0001-0470;Z1198174780

Suppliers and Price of 4-Chloro-6-ethyl-5-fluoropyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-6-ethyl-5-fluoropyrimidine
25g
$ 1455.00

TRC
4-Chloro-6-ethyl-5-fluoropyrimidine
2.5g
$ 185.00

SynQuest Laboratories
4-Chloro-6-ethyl-5-fluoropyrimidine
25 g
$ 125.00

SynQuest Laboratories
4-Chloro-6-ethyl-5-fluoropyrimidine
5 g
$ 75.00

SynQuest Laboratories
4-Chloro-6-ethyl-5-fluoropyrimidine
100 g
$ 450.00

Medical Isotopes, Inc.
4-Chloro-6-ethyl-5-fluoropyrimidine
25 g
$ 2200.00

Medical Isotopes, Inc.
4-Chloro-6-ethyl-5-fluoropyrimidine
2.5 g
$ 650.00

Matrix Scientific
4-Chloro-6-ethyl-5-fluoropyrimidine 95+%
100g
$ 258.00

Matrix Scientific
4-Chloro-6-ethyl-5-fluoropyrimidine 95+%
25g
$ 38.00

Matrix Scientific
4-Chloro-6-ethyl-5-fluoropyrimidine 95+%
5g
$ 23.00

Total 176 raw suppliers

Chemical Property of 4-Chloro-6-ethyl-5-fluoropyrimidine

Chemical Property:

Vapor Pressure:0.272mmHg at 25°C
Refractive Index:1.502
Boiling Point:210.913 °C at 760 mmHg
PKA:-0.45±0.26(Predicted)
Flash Point:81.358 °C
PSA：25.78000
Density:1.286 g/cm³
LogP:1.83150
Storage Temp.:Room temperature.
Solubility.:Chloroform, Ethyl Acetate
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:160.0203541
Heavy Atom Count:10
Complexity:112

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-6-ethyl-5-fluoropyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): 20/21/22-36/37/38:;
Hazard Codes:20/21/22-36/37/38:;
Statements: 20/21/22-36/37/38-41
Safety Statements: 22-36/37/39-45-39-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(C(=NC=N1)Cl)F
Uses 4-Chloro-6-ethyl-5-fluoropyrimidine is a pyrimidine derivative used as a building block in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents. A pyrimidine derivative used as a building block in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.

Technology Process of 4-Chloro-6-ethyl-5-fluoropyrimidine

There total 10 articles about 4-Chloro-6-ethyl-5-fluoropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 137234-87-8
6-ethyl-5-fluoropyrimidin-4(1H)-one

: 137234-74-3
4-chloro-6-ethyl-5-fluoropyrimidine

Guidance literature:: With triethylamine; trichlorophosphate; In dichloromethane; at 48 ℃; for 6h; Product distribution / selectivity; Industry scale; Heating / reflux;

Reference yield: 95.0%

: 137234-87-8
6-ethyl-5-fluoro-4-hydroxypyrimidine

: 137234-74-3
4-chloro-6-ethyl-5-fluoropyrimidine

Guidance literature:: 6-ethyl-5-fluoro-4-hydroxypyrimidine; With triethylamine; trichlorophosphate; In dichloromethane; for 5.5h; Heating / reflux;

With hydrogenchloride; water; In dichloromethane; at 20 ℃;