SAR-407899

Base Information

• Chemical Name: SAR-407899
• CAS No.: 923262-96-8
• Molecular Formula: C₁₄H₁₆N₂O₂*ClH
• Molecular Weight: 280.754
• Hs Code.: 2933990090
• Mol file: 923262-96-8.mol

Synonyms:SAR 407899;SAR407899;SAR-407899;6-(piperidin-4-yloxy)isoquinolin-1(2H)-one hydrochloride;6-(piperidin-4-yloxy)isoquinolin-1(2h)-one hcl;SAR407899 (hydrochloride);SAR407899 HCl;6-(4-Piperidinyloxy)-1(2H)-isoquinolinone hydrochloride

Chemical Property of SAR-407899

Chemical Property:

• PSA: 54.12000
• LogP: 2.78970

Purity/Quality:

97% ^*data from raw suppliers

6-(Piperidin-4-yloxy)isoquinolin-1(2H)-onehydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SAR-407899

There total 5 articles about SAR-407899 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

→ 6-(piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride (923262-96-8)

Guidance literature:

Reference yield:

4-[4-cyano-3-((E)-2-pyrrolidin-1-yl-vinyl)-phenoxy]-piperidine-1-carboxylic acid tert-butyl ester (1417697-15-4) → 6-(piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride (923262-96-8)

Guidance literature:

With hydrogenchloride; In butan-1-ol; at 15 - 65 ℃;

Reference yield:

C27H32N2O5 (1035922-94-1) → 6-(piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride (923262-96-8)

Guidance literature:

C₂₇H₃₂N₂O₅; With trifluoroacetic acid; at 150 ℃; for 2h; microwave reactor;

With hydrogenchloride; In dichloromethane; water;

upstream raw materials:

C₂₇H₃₂N₂O₅

4-[4-cyano-3-((E)-2-pyrrolidin-1-yl-vinyl)-phenoxy]-piperidine-1-carboxylic acid tert-butyl ester

4-fluoro-2-methylbenzonitrile

t-butyl 4-hydroxy piperidine-1-carboxylate