Sulfapyrazine

Base Information Edit

Chemical Name:Sulfapyrazine
CAS No.:116-44-9
Molecular Formula:C10H10 N4 O2 S
Molecular Weight:250.281
Hs Code.:2935009090
NSC Number:41835,25872
UNII:8BE3C727OG
DSSTox Substance ID:DTXSID30151256
Nikkaji Number:J9.348C
Wikidata:Q27270142
Mol file:116-44-9.mol

Synonyms:SULFAPYRAZINE;116-44-9;2-Sulfanilamidopyrazine;Pyrazine, sulfanilamido-;4-Amino-N-(pyrazin-2-yl)benzenesulfonamide;N1-2-Pyrazinylsulfanilamide;4-amino-N-pyrazin-2-ylbenzenesulfonamide;Sulfanilamide, N1-(pyrazinyl)-;N(sup 1)-2-Pyrazinylsulfonilamide;4-Amino-N-pyrazinylbenzenesulfonamide;NSC 25872;NSC 41835;Sulfanilamide, N(sup 1)-(pyrazinyl)-;BRN 0235481;UNII-8BE3C727OG;Benzenesulfonamide, 4-amino-N-pyrazinyl-;8BE3C727OG;NSC25872;NSC41835;NSC-25872;NSC-41835;4-Amino-N-(pyrazinyl)benzenesulfonamide;Benzenesulfonamide, 4-amino-N-2-pyrazinyl-;5-25-10-00140 (Beilstein Handbook Reference);Sulfanilamidopyrazin;SULFAPYRAZINE [MI];SCHEMBL152522;DTXSID30151256;4-Amino-N-pyrazinyl-benzenesulfonamide;LS-31279;4-amino-N-pyrazin-2-yl-benzenesulfonamide;FT-0683938;4-amino-N-(pyrazin-2-yl)benzene-1-sulfonamide;Q27270142

Suppliers and Price of Sulfapyrazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
2 g
$ 578.00

Biosynth Carbosynth
4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
1 g
$ 340.00

Biosynth Carbosynth
4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
500 mg
$ 200.00

Biosynth Carbosynth
4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
250 mg
$ 115.00

Biosynth Carbosynth
4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
100 mg
$ 58.00

Total 7 raw suppliers

Chemical Property of Sulfapyrazine Edit

Chemical Property:

Vapor Pressure:1.41E-09mmHg at 25°C
Melting Point:251°C
Refractive Index:1.6440 (estimate)
Boiling Point:485.5°Cat760mmHg
PKA:pKa 1.78(H2O t = 25 I = 0.05) (Uncertain);6.04(H2O t = 25 I = 0.05) (Uncertain)
Flash Point:247.4°C
PSA：106.35000
Density:1.496g/cm³
LogP:2.59460
Water Solubility.:50mg/L(37 oC)
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:250.05244675
Heavy Atom Count:17
Complexity:333

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Amino-N-pyrimidin-2-ylbenzenesulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1N)S(=O)(=O)NC2=NC=CN=C2

Technology Process of Sulfapyrazine

There total 6 articles about Sulfapyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 4-nitro-N-(pyrazin-2-yl)benzenesulfonamide

: 116-44-9
sulfapyrazine

Guidance literature:: With tin(II) chloride dihdyrate; In ethanol; at 80 ℃; for 0.5h;
DOI:10.3390/molecules25010138

Reference yield:

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 116-44-9
sulfapyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine

2: aqueous HCl

With pyridine; hydrogenchloride;
DOI:10.1021/ja01856a075